Pyrazofurin

Pyrazofurin 구조식 이미지
카스 번호:
30868-30-5
상품명:
Pyrazofurin
동의어(영문):
PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
CBNumber:
CB5276253
분자식:
C9H13N3O6
포뮬러 무게:
259.22
MOL 파일:
30868-30-5.mol
MSDS 파일:
SDS

Pyrazofurin 속성

끓는 점
584.4±50.0 °C(Predicted)
밀도
1.785±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
에 용해됨DMSO, 물 (약간 용해됨)
산도 계수 (pKa)
7.17±0.50(Predicted)
물리적 상태
가루
색상
흰색에서 밝은 갈색까지
optical activity
[α]/D -49 to -39°, c = 0.5 in H2O
안정성
흡습성

안전

Pyrazofurin C화학적 특성, 용도, 생산

용도

Geldanamycin (G304500) derivative.

정의

ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.

효소 저해제

This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.

Pyrazofurin 준비 용품 및 원자재

원자재

준비 용품


Pyrazofurin 공급 업체

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