Pyrazofurin
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Pyrazofurin 속성
- 끓는 점
- 584.4±50.0 °C(Predicted)
- 밀도
- 1.785±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- 에 용해됨DMSO, 물 (약간 용해됨)
- 산도 계수 (pKa)
- 7.17±0.50(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 밝은 갈색까지
- optical activity
- [α]/D -49 to -39°, c = 0.5 in H2O
- 안정성
- 흡습성
안전
Pyrazofurin C화학적 특성, 용도, 생산
용도
Geldanamycin (G304500) derivative.정의
ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.효소 저해제
This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.Pyrazofurin 준비 용품 및 원자재
원자재
준비 용품
Pyrazofurin 공급 업체
글로벌( 28)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Alfa Chemistry | 1-516-6625404 |
support@alfa-chemistry.com | United States | 9171 | 60 |
Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 |
sales@regentsciences.com | China | 9287 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55672 | 58 |
BOC Sciences | 16314854226 |
inquiry@bocsci.com | United States | 9713 | 58 |
Pyrazofurin 관련 검색:
3,5-디메틸피라졸
Pyrazole-3-carboxamide
1-(5-methyl-1H-pyrazol-3-yl)methanamine
5'-deoxypyrazofurin
4-hydroxypyrazole
5-METHYL-1H-PYRAZOLE-3-CARBOXAMIDE
5-methyl-1H-pyrazole-3-carbaldehyde
3-(Aminomethyl)pyrazole
3-ETHYL-1H-PYRAZOLE-5-CARBALDEHYDE
(1H-PYRAZOL-3-YL)METHANOL
4-AMINO-1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXAMIDE HYDROCHLORIDE
2H-PYRAZOLE-3-CARBALDEHYDE
Pyrazofurin
2,2'-Oxydipropanol