Water-white to pale-yellow solid or oily
liquid; pleasant odor. Combustible.
용도
Triphenyl phosphite can be used:
As a source of phosphorus and as a ligand for the synthesis of transition metal phosphide nanoparticles via heating-up process.
To convert alcohols to alkyl halides.
As a peptide coupling agent.
As a low-temperature source of singlet oxygen after forming an adduct with ozone.
To synthesize bromotriphenoxyphosphonium bromide, a brominating agent, by reacting with bromine.
공기와 물의 반응
Insoluble in water.
반응 프로필
Organophosphates, such as Triphenyl phosphite, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
건강위험
Triphenyl phosphite (TPP) is a
skin irritant and sensitizer in humans and is
neurotoxic in laboratory animals.Systemic effects have not been reported in
humans.
Safety Profile
Poison by
intraperitoneal and subcutaneous routes.
Moderately toxic by ingestion. An
experimental eye and severe human skin
irritant. Combustible when exposed to heat
or flame. To fight fire, use CO2, mist, dry
chemical. When heated to decomposition it
emits toxic fumes of POx. See also
PHENOL.
Purification Methods
Its ethereal solution is washed succesively with aqueous 5% NaOH, distilled water and saturated aqueous NaCl, then dried with Na2SO4 and distilled under vacuum after evaporating the diethyl ether. [Walsh J Am Chem Soc 81 3023 1959, Verkade & Coskren in Organo Phosphorus Compounds (Kosolapoff & Maier eds) Wiley Vol 6 pp 211-577 1973, Beilstein 6 IV 695.]
