1-나프틸싸이오요소(안투)
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1-나프틸싸이오요소(안투) 속성
- 녹는점
- 193 °C
- 끓는 점
- 377.6±25.0 °C(Predicted)
- 밀도
- 1.333
- 굴절률
- 1.5500 (estimate)
- 저장 조건
- Poison room
- 용해도
- 아세톤 및 트리에틸렌 글리콜에서 각각 4.3 및 86 g/L(Windholz et al., 1983)
- 산도 계수 (pKa)
- 13.12±0.70(Predicted)
- 물리적 상태
- 결정 또는 결정성 분말
- 색상
- 회색빛~베이지빛 갈색
- 냄새
- 쓴 맛
- 수용성
- 20 °C에서 600 mg/L (quoted, Windholz et al., 1983)
- Merck
- 14,722
- BRN
- 778118
- 노출 한도
- NIOSH REL: TWA 0.3 mg/m3, IDLH 100 mg/m3; OSHA PEL: TWA 0.3 mg/m3
- CAS 데이터베이스
- 86-88-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 30, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+ | ||
---|---|---|---|
위험 카페고리 넘버 | 28-40 | ||
안전지침서 | 28-36/37-45-25-23 | ||
유엔번호(UN No.) | 1651 | ||
OEB | C | ||
OEL | TWA: 0.3 mg/m3 | ||
WGK 독일 | 2 | ||
RTECS 번호 | YT9275000 | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | I | ||
HS 번호 | 29309090 | ||
유해 물질 데이터 | 86-88-4(Hazardous Substances Data) | ||
독성 | Acute oral LD50 for Norwegian rats 6–8 mg/kg (Hartley and Kidd, 1987). | ||
IDLA | 100 mg/m3 | ||
기존화학 물질 | KE-05-1279 | ||
유해화학물질 필터링 | 97-1-175;06-4-18 | ||
함량 및 규제정보 | 물질구분: 유독물질; 혼합물(제품)함량정보: 안투 및 이를 1% 이상 함유한 혼합물 |
1-나프틸싸이오요소(안투) C화학적 특성, 용도, 생산
개요
a-Naphthylthiourea (ANTU; also called DIRAX) is toxic by inhalation, ingestion, or skin contact. Due to its very narrow spectrum of activity, production was discontinued a long time ago. Exposure to ANTU causes pulmonary edema; therefore, it is often used as an experimental pneumotoxin. ANTU is a graycolored, prism-shaped, odorless powder with a bitter taste. It has a molecular weight of 202.28 and melting point of 200 ℃ and does not ignite readily. However, on interaction with potential oxidizing agents, it may cause fire and explosions, which can lead to hazardous decomposition products such as sulfur dioxide, nitrogen dioxide, and carbon monoxide. The structure of ANTU contains the naphthalene chromophore, which absorbs UV light at ~311 nm. This suggests that ANTU can undergo photolysis.화학적 성질
greyish to beige-brown crystals or cryst. powder물리적 성질
Colorless crystals when pure. Technical product is grayish-blue. Odorless solid. Bitter taste.용도
Rodenticide. Specific control for the adult Norway rat; less toxic to other rat species.일반 설명
White crystal or powder; technical product is gray powder. Has no odor but a bitter taste. Used primarily as a rodenticide for control of adult Norway rats. Not produced commercially in the U.S.공기와 물의 반응
Slightly soluble in water.반응 프로필
1-(1-NAPHTHYL)-2-THIOUREA is incompatible with the following: Strong oxidizers, silver nitrate .위험도
Toxic by ingestion건강위험
Moderately toxic: probable oral lethal dose (human) 0.5-5 gm/kg, or between 1 ounce and 1 pint (or l lb.) for 150 lb. person. Chronic sublethal exposure may cause antithyroid activity. Can produce hyperglycemia of three times normal in three hours. People with chronic respiratory disease or liver disease may be especially at risk.화재위험
Emits sulfur dioxide, oxides of nitrogen, and carbon monoxide fumes upon decomposition. 1-(1-NAPHTHYL)-2-THIOUREA reacts with silver nitrate and strong oxidizers. Avoid decomposing heat.Safety Profile
Poison by ingestion and intraperitoneal routes. Moderately toxic to humans by an unspecified route. Questionable carcinogen with experimental tumorigenic data. Mutagenic data. A rodenticide used extensively. Death is caused by pulmonary edema. Chronic toxicity has been known to cause dermatitis and a decrease in the white blood cells. When heated to decomposition it emits toxic fumes of NOx and SOx.잠재적 노출
ANTU or its formulations are used as a rodenticide.Carcinogenicity
ANTU was not carcinogenic in rodent feeding studies.4 Cases of bladder tumors among rat catchers exposed to ANTU have been attributed to b-naphthylamine, a manufacturing impurity of ANTU. In bacterial assays ANTU induced mutations.환경귀착
Chemical/Physical. The hydrolysis rate constant for ANTU at pH 7 and 25°C was determined to be 8 × 10–5/hour, resulting in a half-life of 361 days (Ellington et al., 1988)Emits very toxic fumes of nitrogen and sulfur oxides when heated to decomposition (Lewis, 1990)
저장
α-Naphthalene thiourea should be kept stored in a tightly closed container in a locked poison room, in a cool, dry, well-ventilated area away from incompatible substances.운송 방법
UN1651 Naphthylthiourea, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.Purification Methods
Crystallise ANTU from EtOH. [Beilstein 12 III 2941, 12 IV 3086.]비 호환성
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, silver nitrate.폐기물 처리
Incinerate in a furnace equipped with an alkaline scrubber. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.주의 사항
Workers should use/handle α-naphthalene thiourea with adequate ventilation. During use, dust generation and accumulation should be minimum, and avoid contact with the eyes, skin, and clothing.1-나프틸싸이오요소(안투) 준비 용품 및 원자재
원자재
준비 용품
1-나프틸싸이오요소(안투) 공급 업체
글로벌( 103)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 8672 | 58 |
SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 |
sales@senfeida.com | China | 23048 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
ORGANICA Feinchemie GmbH | +49 3494636389 |
info@organica.de | Germany | 598 | 65 |
Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32360 | 55 |
Alfa Aesar | 400-6106006 |
saleschina@alfa-asia.com | China | 30132 | 84 |
1-나프틸싸이오요소(안투) 관련 검색:
클로피브레이트 신피브레이트 1-나프틸싸이오요소(안투)
ETOFYLLINE CLOFIBRATE
2-HYDROXY-N,N,N,N',N',N'-HEXAMETHYL-1,3-PROPANE DIAMINIUM DI IODIDE
ALUMINUMCLOFIBRATE
phanquone
N-(1-ANTHRYL)THIOUREA
N-(2-METHYL-1-NAPHTHYL)THIOUREA
N-METHYL-N'-(2-METHYL-1-NAPHTHYL)THIOUREA
N-(9-ANTHRYLMETHYL)-N-BENZOYL-N-METHYL-T
4-(1-NAPHTHYL)-3-THIOSEMICARBAZIDE
N-(9-PHENANTHRYL)THIOUREA
2H-NAPHTH[1,2-D]IMIDAZOLE-2-THIONE, 1,3-DIHYDRO-
VITAS-BB TBB000589
N-METHYL-N'-1-NAPHTHYLTHIOUREA
N-BENZOYL-N'-(9-PHENANTHRYL)THIOUREA
N-(1-ANTHRYL)-N'-BENZOYLTHIOUREA