5-Nonyloxytryptamine oxalate

5-Nonyloxytryptamine oxalate 구조식 이미지
카스 번호:
157798-13-5
상품명:
5-Nonyloxytryptamine oxalate
동의어(영문):
Nonyloxytryptamine;JORSCLBFSAAOFR-UHFFFAOYSA-N;Nonyloxytryptamine oxalate >=98% (HPLC);5 Nonyloxytryptamine oxalate,5Nonyloxytryptamine oxalate
CBNumber:
CB53136772
분자식:
C21H32N2O5
포뮬러 무게:
392.5
MOL 파일:
157798-13-5.mol
MSDS 파일:
SDS

5-Nonyloxytryptamine oxalate 속성

저장 조건
room temp
용해도
DMSO: 용해성2mg/mL, 투명(가온)
물리적 상태
가루
색상
흰색에서 노란색, 연한 갈색까지

안전

5-Nonyloxytryptamine oxalate C화학적 특성, 용도, 생산

개요

Nonyloxytryptamine is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dβ with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 cells transfected with the human 5-HT1Dβ receptor. It is selective for 5-HT1Dβ over 5-HT1A for its adenylate cyclase activity, with an EC50 greater than 1 μM for 5-HT1A. It binds to 5-HT1Dβ, 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT2C receptors in vitro (Kis = 1.2-315 nM). Nonyloxytryptamine also inhibits reovirus-mediated cell death in a dose-dependent manner but has no effect on reovirus attachment or internalization.

용도

5-Nonyloxytryptamine Oxalate is a selective 5-HT1B agonist.

Biochem/physiol Actions

Nonyloxytryptamine (5-nonyloxytryptamine) is a potent and selective 5-HT1B receptor agonist. Nonyloxytryptamine is a polysialic acid (PSA) mimick that triggers PSA-mediated functions. Nonyloxytryptamine enhances neurite outgrowth of cultured primary neurons, protects neurons from oxidative stress, enhanced Schwann cell proliferation, reduces migration of astrocytes and enhances myelination in vitro.

5-Nonyloxytryptamine oxalate 준비 용품 및 원자재

원자재

준비 용품


5-Nonyloxytryptamine oxalate 공급 업체

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TargetMol Chemicals Inc.
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Aladdin Scientific
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
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TargetMol Chemicals Inc. 4008200310
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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
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ApexBio Technology --
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