RAS INHIBITORY PEPTIDE

RAS INHIBITORY PEPTIDE 구조식 이미지
카스 번호:
159088-48-9
상품명:
RAS INHIBITORY PEPTIDE
동의어(영문):
VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
CBNumber:
CB5356014
분자식:
C53H91N19O11
포뮬러 무게:
1170.41
MOL 파일:
159088-48-9.mol

RAS INHIBITORY PEPTIDE 속성

밀도
1.52±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
3.31±0.10(Predicted)

안전

WGK 독일 3

RAS INHIBITORY PEPTIDE C화학적 특성, 용도, 생산

개요

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE 준비 용품 및 원자재

원자재

준비 용품


RAS INHIBITORY PEPTIDE 공급 업체

글로벌( 46)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10248 58
Zhejiang Hangyu API Co., Ltd
+8617531972939
anna@api-made.com China 2944 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416
ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696;
info@hanhongsci.com China 42982 64
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15421 60
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
eric@peptidego.com China 6119 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com
meitaochem@126.com China 19105 58
BOC Sciences --
info@bocsci.com USA 0 65

RAS INHIBITORY PEPTIDE 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved