27-DEOXYACTEIN

27-DEOXYACTEIN 구조식 이미지
카스 번호:
264624-38-6
상품명:
27-DEOXYACTEIN
동의어(영문):
Deoxycosimatin;27-DEOXYACTEIN;26-DEOXYACTEIN;DEOXYACTEIN, 27-;23-EPI-26-DEOXYACTEIN;23-EPI-26-Deoxyactein (20 mg);DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P);Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein;β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl;(3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
CBNumber:
CB5365803
분자식:
C37H56O10
포뮬러 무게:
660.83
MOL 파일:
264624-38-6.mol
MSDS 파일:
SDS

27-DEOXYACTEIN 속성

녹는점
253~254℃
밀도
1.32±0.1 g/cm3(Predicted)
저장 조건
Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
클로로포름 (약간 용해됨), 메탄올(매우 약간), 피리딘 (약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
13.03±0.70(Predicted)
색상
흰색에서 황백색까지
안정성
흡습성

안전

27-DEOXYACTEIN C화학적 특성, 용도, 생산

개요

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.

용도

27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.

27-DEOXYACTEIN 준비 용품 및 원자재

원자재

준비 용품


27-DEOXYACTEIN 공급 업체

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