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ENALAPRILAT DIHYDRATE

ENALAPRILAT DIHYDRATE 구조식 이미지

카스 번호:: 84680-54-6

상품명:: ENALAPRILAT DIHYDRATE

동의어(영문):: MK-422;ENALAPRILATE;as dihydrate;ENALAPRILAT USP;MK-422 Dihydrate;Enalaprilate USP25;Vasotec IV Dihydrate;Enalaprilat (300 mg);ENALAPRILAT DIHYDRATE;Enalaprilat (1235274)

CBNumber:: CB5373019

분자식:: C18H26N2O6

포뮬러 무게:: 366.41

MOL 파일:: 84680-54-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 167

ENALAPRILAT DIHYDRATE 속성

녹는점: 151-159°C

알파: [α]D25 -53.0～-56.0゜ (c=1, CH3OH) (Calculated on dehydrous basis)

저장 조건: 2-8°C

용해도: H2O: 60°C에서 용해성 14mg/mL(5분간 따뜻하게 유지)

색상: 흰색에서 황백색까지

CAS 데이터베이스: 84680-54-6(CAS DataBase Reference)

EPA: L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-, hydrate (1:2) (84680-54-6)

안전

위험 및 안전 성명

WGK 독일	3
RTECS 번호	TW3590600
HS 번호	2933995300

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드

예방조치문구:

NFPA 704

	0
2		0

ENALAPRILAT DIHYDRATE C화학적 특성, 용도, 생산

개요

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat is the active metabolite of enalapril , an ACE inhibitor with roles in the management of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies.. Enalaprilat is esterified with ethanol to produce enalapril in order to enable oral activity and subsequently metabolized in vivo to the active form by various esterases. Enalaprilat is reported to inhibit ACE activity with an IC₅₀ value of 5.8 nM in vitro.

화학적 성질

White Solid

정의

ChEBI: The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients wi h nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.

ENALAPRILAT DIHYDRATE 준비 용품 및 원자재

원자재

준비 용품

ENALAPRILAT DIHYDRATE 공급 업체

글로벌( 167)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7377	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9571	58

ENALAPRILAT DIHYDRATE 관련 검색:

Enalaprilat Triphosgene Ethyl trans-3-Benzoylacrylate Enalapril EP IMpurity A (SSR) L-Proline (R,S,S)-Enalapril L-Alanine Enalapril diketopiperazine (αS)-Cyclohexanebutanoic Acid α-[[(1S)-1-Carboxyethyl]aMino] cyclohexanebutanoic Acid α-Ethyl Ester Ethyl 3-benzoylacrylate Phenylsilane CHLOROPHENYLSILANE 97 Dimethylimidazole Phenyltrichlorosilane MOEXIPRIL HYDROCHLORIDE Fosinopril sodium CILAZAPRIL Belinostat (PXD101)