하이포크산틴
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하이포크산틴 속성
- 녹는점
- >300 °C (lit.)
- 끓는 점
- 250.36°C (rough estimate)
- 밀도
- 1.4295 (rough estimate)
- 굴절률
- 1.8500 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 1 M NaOH: 25 mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.7(at 25℃)
- 색상
- 무색~황색~갈색, 보관 시 순도 손실 없이 어두워집니다.
- 냄새
- 냄새 없는
- 수용성
- 실질적으로 불용성
- Merck
- 14,4869
- BRN
- 5811
- InChIKey
- FDGQSTZJBFJUBT-UHFFFAOYSA-N
- LogP
- -0.910 (est)
- CAS 데이터베이스
- 68-94-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-22-40 | ||
| 안전지침서 | 22-24/25-37/39-26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | UP0791000 | ||
| 위험 참고 사항 | Harmful | ||
| TSCA | Yes | ||
| HS 번호 | 29335990 | ||
| 독성 | LD50 intraperitoneal in mouse: 750mg/kg |
하이포크산틴 C화학적 특성, 용도, 생산
개요
Hypoxanthine is a naturally occurring purine derivative and intermediate in the synthesis of uric acid. It is elevated in the spinal fluid of patients with Lesch-Nyhan syndrome, a metabolic disorder whose symptoms include cerebral palsy, cognitive deficits, motor dysfunction, self-mutilation, and hyperuricemia. Injection of hypoxanthine (10 μM) increases succinate dehydrogenase and complex II activities and decreases cytochrome c oxidase activity, resulting in neuroenergetic impairment, ATP depletion, and cellular apoptosis in rat striatum. It is also used to induce hyperuricemia in mice for use in the development of hypouricemic agents.화학적 성질
White to off-white powder용도
A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals정의
ChEBI: A purine nucleobase that consists of purine bearing an oxo substituent at position 6.일반 설명
Hypoxanthine (6-hydroxypurine), a purine derivative is a naturally occurring compound. It is the deaminated form of adenine and a breakdown product of adenosine monophosphate (AMP).Safety Profile
Moderately toxic by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NoxPurification Methods
Crystallise it from hot water and dry it at 105o. [Beilstein 26 II 252, 26 III/IV 2081.]하이포크산틴 준비 용품 및 원자재
원자재
준비 용품
6-Dimethylaminopurine
6-N-HEPTYLMERCAPTOPURINE
아데닌
6-머캡토퓨린
6-N-HEXYLAMINOPURINE
6-ETHOXYPURINE
6-CYANOPURINE
6-benzylaminopurine
6-ETHYLMERCAPTOPURINE
에이사이클로비르
6-Bromopurine
N6-CYCLOHEXYLADENOSINE
6-메르캅토퓨린
N-(2-Hydroxyethyl)adenosine
6-N-BUTOXYPURINE
퓨린
자료없음
6-Iodopurine
6-benzylaminopurine hydrochloride
하이포크산틴 공급 업체
글로벌( 759)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 298 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
하이포크산틴 관련 검색:
5′-이노신산이나트륨 퓨린 요산 6-메르캅토퓨린 구아닌 크산틴 이노신 구아노신 하이포크산틴 N2-아이소부티릴-5'-O-(4,4'-디메톡시트리틸)-2'-데옥시구아노신
6-Mercaptopurine disulfide
GUANERAN
Ethanone, 1-[6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purin-9-yl]-
8-Methyl-7H-purin-6-ol
9H-Purine, 9-β-D-arabinofuranosyl-6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI)
4,5-Dichloroimidazole
1,7-DIHYDRO-2-METHYL-6-PURINONE