Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.
정의
ChEBI: A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
일반 설명
Crystals or white powder.
공기와 물의 반응
Insoluble in water.
반응 프로필
Strong reducing agents will produce toxic gases ammonia and hydrogen sulfide.
화재위험
Flash point data for Hydrochlorothiazide are not available but Hydrochlorothiazide is probably combustible.
Safety Profile
Poison bp
intraperitoneal and intravenous routes.
Moderately toxic by ingestion and
subcutaneous routes. Human systemic
effects by ingestion: sodum level changes,
chlorine level changes, acute pulmonary
edema, nausea or vomiting. Experimental
reproductive effects. Questionable
carcinogen with experimental tumorigenic
data. Mutation data reported. A duetic.
When heated to decomposition it emits very
toxic fumes of SOx, Cl-, and NOx.
