Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
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Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine 속성
- 끓는 점
- 733.7±60.0 °C(Predicted)
- 밀도
- 1.221
- 저장 조건
- Store at -15°C to -25°C.
- 산도 계수 (pKa)
- 3.47±0.10(Predicted)
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine C화학적 특성, 용도, 생산
용도
N-alpha-Fmoc-N-beta-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic Acid is used in the synthesis of phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors. It is also used to prepare peptidomimetic ligands for α4β1 integrin on Jurkat T-leukemia cells.일반 설명
This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3].When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4].
The product number for this product was previously 04-12-1195.
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Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine 준비 용품 및 원자재
원자재
준비 용품
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine 공급 업체
글로벌( 77)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 |
sales@alphabiopharm.com | China | 886 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 |
CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 |
wuqiuyan@glschina.com | China | 2975 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29474 | 58 |
| BOC Sciences | +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 |