GLY-ARG-GLY-ASP-SER

GLY-ARG-GLY-ASP-SER 구조식 이미지
카스 번호:
96426-21-0
상품명:
GLY-ARG-GLY-ASP-SER
동의어(영문):
GRGDS;GRGDS 1/2ACOH 2H2O;GLY-ARG-GLY-ASP-SER;H-GLY-ARG-GLY-ASP-SER-OH;Gly-Arg-Gly-Asp-Ser (TFA);GRGDS, fibrinogen fragment;GLY-ARG-GLY-ASP-SER ACETATE;GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O;Gly-Arg-Gly-Asp-Ser >=97% (HPLC);H-Gly-Arg-Gly-Asp-Ser-OH TFA salt
CBNumber:
CB5414527
분자식:
C17H30N8O9
포뮬러 무게:
490.47
MOL 파일:
96426-21-0.mol
MSDS 파일:
SDS

GLY-ARG-GLY-ASP-SER 속성

밀도
1.66±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO : 100 mg/mL (203.89 mM);Water : 33.33 mg/mL (67.96 mM)
산도 계수 (pKa)
2.85±0.10(Predicted)
물리적 상태
백색 내지 황백색의 동결건조된 고체
시퀀스
H-Gly-Arg-Gly-Asp-Ser-OH

안전

WGK 독일 3

GLY-ARG-GLY-ASP-SER C화학적 특성, 용도, 생산

용도

Gly-Arg-Gly-Asp-Ser has been used-
  • as an antigen to determine whether integrin α4 or α5 hinders the adhesion of day 3 postirradiation thymocytes to thymic epithelial cells, in mice
  • for the treatment of collagen IV-coated dishes to study the role of integrins α1, αv, β1, and β3 in Sca-1+ progenitor cell differentiation into SMCs (smooth muscle cells)
  • as a blocking peptide for the pre-incubation of Nisseria meningitides strains, to perform blocking experiments to study the interactions between these bacterial strains and fibronectin
  • for the pre-treatment of EL-4 cells infected by AdCMV-GFP (cytomegalovirus-green fluorescent protein), to study whether interaction with cellular integrins is essential for the transduction of adenovirus

일반 설명

Gly-Arg-Gly-Asp-Ser peptide sequence is identical to the cell-binding region of fibronectin protein. Arg-Gly-Asp (RGD) region is found in various proteins, and is crucial for facilitating cell-adhesive activity.

Biochem/physiol Actions

Antagonist of integrin function

GLY-ARG-GLY-ASP-SER 준비 용품 및 원자재

원자재

준비 용품


GLY-ARG-GLY-ASP-SER 공급 업체

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