HUMAN IL-13

HUMAN IL-13 C화학적 특성, 용도, 생산

일반 설명

Interleukin-13 (IL-13) is an immunoregulatory cytokine produced primarily by activated T-helper 2 (Th2) cells,and also by mast cells and natural killer (NK) cells. The gene encoding it is localized on human chromosome 5q31. Human and murine IL-13 is cross-species reactive. Recombinant human IL-13 is a 12.6kDa protein consisting of 115 amino acid residues.

Biochem/physiol Actions

Interleukin-13 (IL-13) has a role in immune activities against infections and influences the function of various cells taking part in the same. It has been studied to be overexpressed in glioblastoma tumors and cell lines. IL-13 stimulates fibrosis in many infectious diseases. Targeted deletion of IL-13 in mice resulted in impaired T-helper 2 (Th2) cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukins-1β, -6 and -8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of immunoglobulin E (IgE). Blocking of IL-13 activity inhibits the pathophysiology of asthma.

HUMAN IL-13 준비 용품 및 원자재

원자재

준비 용품

HUMAN IL-13 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29797	68
Chengdu Youngshe Chemical Co., Ltd.	028-62328193 17380623303	Caroline@youngshechem.com	China	2348	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58
Shanghai Kanglang Biotechnology Co., Ltd.	021-61998208 18217752821	sales@klbio.cn	China	9617	58
Absin Bioscience Inc.	021-38015121 15000105423	chenjw@absin.cn	China	24734	58
Wuhan Chemstan Biotechnology Co., Ltd.	15926423062	422450190@qq.com	China	10132	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
Shanghai fantai biology science and technology co., ltd	15601885736	2114786541@qq.com	China	206	58
Abmole Bioscience Inc.	021-50967598 02150967598	sales@abmole.cn	China	4495	58

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