인돌린
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인돌린 속성
- 녹는점
- -21 °C
- 끓는 점
- 220-221 °C (lit.)
- 밀도
- 1.063 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.592(lit.)
- 인화점
- 199 °F
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 5g/L
- 물리적 상태
- 액체 (투명)
- 산도 계수 (pKa)
- 5.20±0.20(Predicted)
- 색상
- 클리어 다크 브라운
- 냄새
- a mild, delicate, but extremely tenacious floral odor
- 수용성
- 5g/L(20℃)
- 감도
- Light Sensitive
- BRN
- 111915
- CAS 데이터베이스
- 496-15-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 23-24/25-37/39-26 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | NL6906300 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | Yes | ||
| HS 번호 | 29339990 |
인돌린 C화학적 특성, 용도, 생산
화학적 성질
?2,3-Dihydroindole [496-15-1], indoline C8H9N, Mr 119.16, bp 229 – 230 ℃(101.3 kPa), is a colorless liquid, which is volatile in steam and soluble in diethyl ether, acetone, and benzene, but only slightly soluble in water. Indoline is obtained by hydrogenation of indole or by catalytic cyclodehydration of 2-(2-aminophenyl)ethanol. A range of pharmaceuticals, as well as fungicides and bactericides, can be produced from indoline.용도
As an indole derivative, Indoline can be used in the preparation of various medicinal compounds such as potential α1-adrenoceptor (α1-AR) antagonists.Synthesis Reference(s)
Journal of the American Chemical Society, 96, p. 7812, 1974 DOI: 10.1021/ja00832a035Synthetic Communications, 13, p. 489, 1983 DOI: 10.1080/00397918308081827
Synthesis
Indolene is manufactured from (theoretically) 2 Mol. Indole plus 1 Mol. Hydroxycitronellal by condensation under heating. The proportions may vary slightly, and it is common practice to add Diethyl phthalate to the mixture prior to heating, so that the condensation product is somewhat protected against local overheating, and the finished product becomes light of color and fairly pourable at room temperature.인돌린 준비 용품 및 원자재
원자재
준비 용품
2,3-디히드로-1H-인돌-5-카르복실산
5-시아노-2,3-디하이드로-1H-인돌
1-아세틸-5-아미노-2,3-디하이드로-(1H)-인돌
1-아세틸-5-브로모인돌린
5-AMINOINDOLE HYDROCHLORIDE
INDOLINE-7-CARBOXYLIC ACID
5-브로모인돌린
6-bromoindoline
6-니트로인돌
1-아세틸-5-니트로인돌린
6-아미노인돌
인돌
4-브로모-2,3-DIHYDRO-1H-인돌
7-bromoindoline
2-(2,3-Dihydro-1H-indol-1-yl)ethanol
5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile
1-(2,3-dihydro-1H-indol-1-yl)-2-Propen-1-one
인돌린 공급 업체
글로벌( 485)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49732 | 58 |
| Hangzhou Verychem Science And Technology Co.Ltd | +86-86-57188162785 13606544505 |
lucy@verychem.com | China | 1081 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15531157085 +86-15531157085 |
abby@chuanghaibio.com | China | 8807 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12821 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20254 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 |
info@dakenam.com | China | 19844 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21631 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1803 | 55 |
| AB PharmaTech,LLC | 323-480-4688 |
sales@acrospharmatech.com | United States | 989 | 55 |