3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE C화학적 특성, 용도, 생산
용도
Methyl-3,4-dephostatin has been used as:
an inhibitor for methyltransferases
a kinase-related inhibitor for human transglutaminase
a cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein
Biochem/physiol Actions
Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI).
3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE 준비 용품 및 원자재
