O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI
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O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI 속성
- 녹는점
- 172-175°C
- 밀도
- 1.53
- 저장 조건
- -20°C
- 용해도
- DMSO에 용해됨(최대 35mg/ml)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 11.85±0.70(Predicted)
- 색상
- 하얀색
- BRN
- 4274031
- 안정성
- 수분 및 온도에 민감함
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| WGK 독일 | 3 | ||
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| HS 번호 | 29329990 |
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI C화학적 특성, 용도, 생산
개요
Proteins can be modified post-translationally by the addition of O-linked N-acetylglucosamine (O-GlcNAc). Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT) is a β-N-acetylglucosaminidase that removes GlcNAc from O-glycosylated proteins. PUGNAc is a (phenylcarbamoyl)oxime analog of GlcNAc that reversibly inhibits NCOAT (Ki = 40-110 nM). It also less potently inhibits other hexosaminidases and exochitinases. (Z)-PUGNAc is a stereoisomer of PUGNAc that is a more potent inhibitor of NCOAT than the (E) isomer, both in vitro and in cells.화학적 성질
White to Off-White Solid용도
An inhibitor of O-GlcNAcase, hexosaminidase A, and hexosaminidase B생물학적 활성
O -GlcNAc- β - N -acetylglucosaminidase ( O -GlcNAcase) and β -hexosaminidase inhibitor (K i values are 46 and 36 nM respectively) that increases O -GlcNAc levels ~ 2-fold in HT29 cells. Z -linked isomer is more potent than the E isomer.O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI 준비 용품 및 원자재
원자재
O-(2-ACETAMIDO-3,4,6-TRI-O-ACETYL-D-GLUCOPYRANOSYLIDENE)AMINO N-PHENYL CARBAMATE
2-ACETAMIDO-2-DEOXY-D-GLUCONHYDROXIMO-1,5-LACTONE 1-N,3,4,6-TETRAACETATE
2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE
준비 용품
O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI 공급 업체
글로벌( 95)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 |
info@fortunachem.com | China | 5988 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 |
sales@bicbiotech.com | China | 6000 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI 관련 검색:
5-히드록시펜탄알 옥심
3-METHYLADENINE
Tris(2-carboxyethyl)phosphine hydrochloride
CAL-101
PHOSPHATIDYLETHANOL
AMINO ACID HYDROXAMATES DL-NORVALINE HYDROXAMATE
2-ACETAMIDO-2-DEOXY-D-GLUCONHYDROXIMO-1,5-LACTONE
4-HYDROXY-BUTYRIMIDIC ACID ETHYL ESTER
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE
Ethyl acetohydroxamate
AMINO ACID HYDROXAMATES GLYCINE HYDROXAMATE
O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI
AMINO ACID HYDROXAMATES DL-THREONINE HYDROXAMATE