장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음(노출되어도 특정 표적장기 독성을 일으키지 않는다는 결정적인 노출경로가 있다면 노출경로를 기재)
특정 표적장기 독성 - 2회 노출
구분 2
경고
P260, P264, P270, P309+P311, P405,P501
예방조치문구:
P260
분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P264
취급 후에는 손을 철저히 씻으시오.
P264
취급 후에는 손을 철저히 씻으시오.
P270
이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P302+P352
피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2
0
D(-)3-PHOSPHOGLYCERIC ACID DISODIUM SALT C화학적 특성, 용도, 생산
용도
D-(-)-3-Phosphoglyceric Acid Disodium Salt can be used as a hydrothermal treatment.
Biochem/physiol Actions
3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.
Purification Methods
It is best purified by conversion to the Ba salt by precipitation with BaCl2, which is recrystallised three times before conversion to the sodium salt. The Ba salt (9.5g) is shaken with 200mL of a 1:1 slurry of Dowex 50 (Na+ form) for 2hours. The mixture is filtered, and the resin is washed with H2O (2 x 25mL). The combined filtrates (150mL) are adjusted to pH 7.0 and concentrated in vacuo to 30-40mL and filtered if not clear. Absolute EtOH is added to make 100mL, and then n-hexane is added whereby a white solid and/or a second phase separates. When set aside at room temperature, complete precipitation of the Na salt as a solid occurs. The salt is removed by centrifugation, washed with Me2CO, dried in air then in an oven at 55o to give a stable powder (4.5g). It did not lose weight when dried further over P2O5 at 78o/8hours. The high rotation in the presence of (NH4)6Mo7O24 is not very sensitive to the concentration of molybdate or pH as it did not alter appreciably in 1/3 volume between 2.5 to 25% (w/v) of molybdate or at pH values ranging between 4 and 7. [Cowgill Biochim Biophys Acta 16 613 1955, Embdan et al. Hoppe Seyler's Z Physiol Chem 230 20 1934, Beilstein 3 IV 1051.]
D(-)3-PHOSPHOGLYCERIC ACID DISODIUM SALT 준비 용품 및 원자재
