FAMOTI디NE
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FAMOTI디NE 속성
- 녹는점
- 163-164°C
- 끓는 점
- 562.7±60.0 °C(Predicted)
- 밀도
- 1.5111 (rough estimate)
- 굴절률
- 1.7400 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 물에 아주 약간 녹고, 빙초산에 잘 녹고, 무수 에탄올에 아주 조금 녹고, 에틸 아세테이트에는 거의 녹지 않습니다. 묽은 무기산에 용해됩니다.
- 산도 계수 (pKa)
- pKa 6.76(H2O t=23.0) (Uncertain)
- 색상
- 흰색에서 황백색까지
- 수용성
- 1.1mg/mL
- BCS Class
- 3
- 안정성
- 감광성
- InChI
- InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
- InChIKey
- XUFQPHANEAPEMJ-UHFFFAOYSA-N
- SMILES
- C(NS(N)(=O)=O)(=N)CCSCC1=CSC(NC(N)=N)=N1
- CAS 데이터베이스
- 76824-35-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-45-61 | ||
| 안전지침서 | 22-24/25-53-45-36/37/39 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | UA2300000 | ||
| HS 번호 | 29341000 | ||
| 유해 물질 데이터 | 76824-35-6(Hazardous Substances Data) | ||
| 독성 | LD50 i.v. in mice: 244.4 mg/kg (Yasufumi) | ||
| 기존화학 물질 | KE-01425 |
FAMOTI디NE C화학적 특성, 용도, 생산
개요
Famotidine is a competitive histamine H2-receptor antagonist, and the main pharmacodynamic effect of famotidine is to cause the inhibition of gastric secretion. Famotidine on decomposition releases toxic products such as carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), and sulphur oxides (SO2, SO3). Famotidine is a medication that is available both in prescription and over-the-counter forms. It is used to treat conditions related to the oesophagus, stomach, and intestines. Some specific famotidine is used for the treatment of duodenal ulcers, gastric ulcers (stomach ulcers), gastroesophageal reflux disease (GERD), and pathological hypersecretory conditions that occur when stomach acid is secreted/ produced in very large quantities, an abnormal health condition called ‘Zollinger-Ellison syndrome’.화학적 성질
White Powder용도
Contact dermatitis from famotidine, a H2 -receptor agonist, was described in a nurse. In industry, three cases were reported due to intermediates of synthesis, 2- diamino-ethylene-amino-thiazolyl-methylenethiourea-dichloride and 4-chloromethyl-2-guanidinothiazolenitrochloride.일반 설명
Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
색상 색인 번호
Contact dermatitis in a nurse from famotidine, an H2-receptor agonist, was described. In industry, three cases were reported due to intermediates of the synthesis of 2-diamino-ethylene-amino-thiazolyl-methylenethio urea-dichloride, and 4-chloromethyl-2-guanidinothiaz ole-nitrochloride.Clinical Use
Famotidine is a histamine H2-antagonist more potent than cimetidine and ranitidine. Administered once or twice daily, it is useful in the treatment of gastric, duodenal and anastomotic ulcers, upper gastrointestinal tract hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome. Like ranitidine, it is lacking in antiandrogenic effects.FAMOTI디NE 준비 용품 및 원자재
원자재
준비 용품
FAMOTI디NE 공급 업체
글로벌( 669)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Kangcang new material Technology Co., LTD | +8619133911216 |
fanfan@kangcang.com.cn | China | 338 | 58 |
| Liaoning Pharmaceutical Innovation Co., Ltd | +8616588669988 |
sales@pipharma.com.cn | China | 148 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Rixing Chemical CO.,LTD | +86-13237129059 -13237129059 |
sales@rixingchemi.com | CHINA | 229 | 55 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 |
bruce@xrdchem.cn | CHINA | 566 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Casorganics US Corp | +17326109938 |
sales@casorganics.com | CHINA | 174 | 58 |