벤조페논

벤조페논 속성

벤조페논 MSDS

Benzophenone

벤조페논 C화학적 특성, 용도, 생산

용도

1. Benzophenone 는 같은 잉크, 이미징, UV 경화 애플리케이션에서 초기자 사진 및 인쇄 산업에서 코팅 선택을 취소으로 사용할 수 있습니다. Benzophenone 손상 향기에서 자외선 (UV)을 방지 하 고 향수, 비누 등 제품 색상. 2. Benzophenone 포장 폴리머 또는 그 내용을 사진-저하를 막을 UV 차단 로 플라스틱 포장에 추가할 수 있습니다. 그것의 사용에는 명확한 유리 또는 플라스틱 (예: 피트 물 병)에 제품을 포장 하는 제조 업체 수 있습니다. 그것 없이, 불투명 또는 어두운 포장 필요한 것입니다. 3. 생물 학적 응용 프로그램에서 benzophenones 사용 되었습니다 광범위 하 게 파악 하 고 펩타이드-단백질 상호 작용 지도 photophysical 프로브로. 4. Benzophenones 제약 중간체, 화장품 향수 및 살충제로 사용할 수 있습니다.

화학적 성질

Benzophenone is a combustible, white, crystalline solid with a rose-like odor. soluble in ethanol, ether, chloroform and other organic solvents and monomers, insoluble in water. It is a free radical photoinitiator, mainly used in free radical UV curing systems, such as coatings, inks, adhesives, etc. It can be prepared in several ways, for example, by Friedel–Crafts reaction of benzene and benzoyl chloride with aluminum chloride, or of benzene and carbon tetrachloride, and oxidation of diphenylmethane.

출처

Benzophenone has been found in various fruits, including Vitis vinifera L., black tea, cherimoya (Annona cherimola), mountain papaya (Carica pubescens), and soursop (Annona muricata L.).

용도

Benzophenone is used as a synthetic intermediate for manufacture of pharmaceuticals and agricultural chemicals. It is also used as a photoinitiator in UV-curable printing inks, as a fragrance in perfumes, as a flavor enhancer in foods. Benzophenone can be added as a UV-absorbing agent to plastics, lacquers, and coatings at concentrations of 2–8%.

생산 방법

Benzophenone is commercially synthesized by the atmospheric oxidation of diphenylmethane using a catalyst of copper naphthenate. Alternatively, it can be produced by a Friedel–Crafts acylation of benzene using either benzoyl chloride or phosgene in the presence of aluminum chloride .

정의

ChEBI: Benzophenone is the simplest member of the class of benzophenones, being formaldehyde in which both hydrogens are replaced by phenyl groups. It has a role as a photosensitizing agent and a plant metabolite.

일반 설명

Benzophenone(119-61-9) appears as white solid with a flowery odor. May float or sink in water. It is a widely used building block in organic chemistry, being the parent diarylketone.

공기와 물의 반응

Insoluble in water.

반응 프로필

Ketones, such as Benzophenone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. Benzophenone can react with oxidizing materials.

건강위험

Ingestion causes gastrointestinal disturbances. Contact causes eye irritation and, if prolonged, irritation of skin.

화재위험

Flash point data for Benzophenone are not available, but Benzophenone is probably combustible.

색상 색인 번호

Unsubstituted benzophenone is largely used in chemical applications. It acts as a marker for photoallergy to ketoprofen.

Safety Profile

Moderately toxic by ingestion andintraperitoneal routes. Combustible when heated.Incompatible with oxidizers. When heated todecomposition it emits acrid and irritating fumes.

잠재적 노출

Benzophenone is used in UV curing of inks and coatings; as an intermediate; as an odor fixative in fragrances, flavoring, soaps; in the manufacture of pharmaceuticals and insecticides; in organic syntheses.

Carcinogenicity

Lifetime dermal carcinogenicity studies in mice and rabbits did not show any tumor excess in the treated animals. Female Swiss mice and New Zealand White rabbits of both sexes were treated dermally with 0, 5, 25, or 50% of benzophenone (0.02 mL) twice a week for 120 or 180 weeks. Weekly examination of the rabbits did not reveal any reduction in survival or appearance of tumors. Mice treated with benzophenone did not show any excess in the number of tumor-bearing animals or in total number of tumors compared to untreated control animals. Although three skin tumors were observed in the benzophenone- treated mice (one case of squamous cell carcinoma and two cases of squamous cell papilloma), there were also three tumors (one carcinoma and toe papillomas) observed in the control animals.

신진 대사

Benzophenone's main metabolic pathway in the rabbit is by reduction to benzhydrol, which is excreted conjugated with glucuronic acid(Williams, 1959).

운송 방법

UN1224 Ketones, liquid, n.o.s., Hazard Class: 3; Labels: 3—Flammable liquid, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9—Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise it from MeOH, EtOH, cyclohexane, *benzene or pet ether, then dry in a current of warm air and store it over BaO or P2O5. It is also purified by zone melting and by sublimation [Itoh J Phys Chem 89 3949 1985, Naguib et al. J Am Chem Soc 108 128 1986, Gorman & Rodgers J Am Chem Soc 108 5074 1986, Ohamoto & Teranishi J Am Chem Soc 108 6378 1986, Naguib et al. J Phys Chem 91 3033 1987]. [Beilstein 7 III 2048, 7 IV 1357.]

비 호환성

Oxidizing materials, such as dichromates and permanganates.

벤조페논 준비 용품 및 원자재

원자재

준비 용품

벤조페논 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Across Biotech Jinan Co LTD	+8613031735486	frank@acrossbiotech.com	China	105	58
Wuhan Biet Co., Ltd.	+8617320528784	min@biet.com.cn	China	41	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	20000	58
Shanghai Bojing Chemical Co.,Ltd.	+86-86-02137122233 +8613795318958	bj1@bj-chem.com	China	298	55
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1100	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Hebei Jingbo New Material Technology Co., Ltd	+8619931165850	hbjbtech@163.com	China	1000	58
Xiamen Wonderful Bio Technology Co., Ltd.	+8613043004613	Sara@xmwonderfulbio.com	China	305	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58

벤조페논 관련 검색: