피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
3
2
0
3-Ethoxyacryloyl chloride C화학적 특성, 용도, 생산
화학적 성질
light yellow liquid
용도
Used as an intermediate in organic synthesis.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 13, p. 1015, 1976 DOI:10.1002/jhet.5570130515 Synthesis, p. 1079, 1993
Synthesis
To a solution of ethyl 3,3-diethoxypropionate (20 g) in water (50 mL) was added sodium hydroxide (5 g) at room temperature and the reaction was heated to 110°C and stirred at this temperature for 1 hour. Then the reaction system was naturally cooled to room temperature, diluted with water (2L), extracted with ethyl acetate (1L), the extract was washed with saturated brine (1L), dried over anhydrous sodium sulfate and filtered; the filtrate was directly concentrated to obtain To the crude was added thionyl chloride (30 mL) and the reaction was heated to 70°C and stirring was continued at this temperature for one hour. After the reaction, the reaction solution was directly concentrated under reduced pressure to obtain a brown solid 3-Ethoxyacryloyl chloride (14 g, yield 90%).
