Calpain Inhibitor I
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Calpain Inhibitor I 속성
- 녹는점
- 182 °C
- 끓는 점
- 510.42°C (rough estimate)
- 밀도
- 1.1322 (rough estimate)
- 굴절률
- 1.6300 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 용해될 수 있다
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 13.53±0.46(Predicted)
- 색상
- 하얀색
- 수용성
- 디메틸설폭사이드, 에탄올, 메탄올에 용해됩니다. 물 및 수성 완충액에 불용성입니다.
- BRN
- 7656053
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 유해·위험 문구: |
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| 예방조치문구: |
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Calpain Inhibitor I C화학적 특성, 용도, 생산
화학적 성질
white to off-white powder용도
It inhibits apoptosis in thymocytes and metamyelocytes. It also inhibits cell cycle progression at the G1/S border and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. ALLN inhibits the proteolysis of IκBα and IκBβ by the ubiquitin-proteasome complex. ALLN also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.정의
ChEBI: A tripeptide composed of N-acetylleucyl, leucyl and norleucinal residues joined in sequence.일반 설명
Calpain Inhibitor I is a strong, competitive inhibitor of the Ca2+-dependent neutral cysteine proteases calpain I and calpain II.생물학적 활성
Calpain inhibitor (IC 50 = 0.09 μ M) that activates p53-dependent apoptosis in tumor cell lines. Increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro . Also attenuates ischemia/reperfusion injury in cardiomyocytes, hepatocytes and renal tubular cells through downregulation of iNOS and COX-2 expression.Calpain Inhibitor I 준비 용품 및 원자재
원자재
준비 용품
Calpain Inhibitor I 공급 업체
글로벌( 117)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 |
admin01@hsnm.com.cn | China | 2118 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Calpain Inhibitor I 관련 검색:
Calpain Inhibitor I
CALPAIN INHIBITOR I,CALPAIN INHIBITOR
CALPAIN INHIBITOR IV
CALPAIN INHIBITOR III
MET-ALA-GLY-ARG-SER-GLY-ASP-SER-ASP-GLU-ASP-LEU-LEU-LYS-ALA-VAL
(TYR0)-KALIURETIC PEPTIDE (HUMAN)
H-PRO-ALA-VAL-ASP-LEU-LEU-LYS-ASN-TYR-MET-GLN-LEU-GLY-LYS-GLN-OH
ASP-GLU-ASP-LEU-LEU-LYS-ALA-VAL-ARG-LEU-ILE-LYS-PHE-LEU-TYR-GLN-SER-ASN
PEPTITERGENT PD1
H-PRO-PRO-GLU-ASP-PRO-ALA-VAL-ASP-LEU-LEU-LYS-ASN-TYR-MET-GLN-LEU-GLY-LYS-GLN-GLN-OH
H-MET-PRO-THR-ALA-PRO-PRO-GLU-ASP-PRO-ALA-VAL-ASP-LEU-LEU-LYS-OH
KALIURETIC PEPTIDE (HUMAN)
SPFK
H-SER-LEU-LEU-LYS-OH
H-PRO-PRO-GLU-ASP-PRO-ALA-VAL-ASP-LEU-LEU-LYS-ASN-TYR-MET-GLN-OH
PREPRO-ANF (104-116), HUMAN
PSTAIR peptide
GLU-ASP-LEU-LEU-LYS-ALA-VAL-ARG-LEU-ILE-LYS