알부테롤 황산염
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알부테롤 황산염 속성
- 녹는점
- 180 °C
- 인화점
- 250 °C
- 저장 조건
- 2-8°C
- 용해도
- 1 M NaOH: 가용성 50 mg/ml, 투명하거나 약간 흐릿함, 황록색
- 색상
- 하얀색
- 수용성
- 물과 1M 수산화나트륨(50mg/ml)에 용해됩니다.
- Merck
- 216
- BCS Class
- 1
- InChI
- InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
- InChIKey
- OVICLFZZVQVVFT-UHFFFAOYSA-N
- SMILES
- CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O
- CAS 데이터베이스
- 51022-70-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 43-22 | ||
| 안전지침서 | 36/37-36 | ||
| 유엔번호(UN No.) | 2811 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | ZE4400000 | ||
| HS 번호 | 29225090 | ||
| 기존화학 물질 | KE-11364 |
알부테롤 황산염 C화학적 특성, 용도, 생산
개요
Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.화학적 성질
Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol.용도
Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications.정의
ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol.일반 설명
Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA).생물학적 활성
Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.Mode of action
Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.참고 문헌
https://en.wikipedia.org/wiki/Salbutamolhttps://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm
알부테롤 황산염 준비 용품 및 원자재
원자재
준비 용품
알부테롤 황산염 공급 업체
글로벌( 520)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 |
market02@senwayer.com | China | 874 | 58 |
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 |
Ethan@dornechem.com | China | 293 | 58 |
| Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 |
ada@sh-teruiop.com | China | 892 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 |
hanson@sdhanjiang.com | China | 1527 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 524 | 58 |
| Shanghai Aosiris new Material Technology Co., LTD | +8615139564871 |
wrjmoon2000@163.com | China | 354 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9352 | 55 |