티미딘
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티미딘 속성
- 녹는점
- 186-188 °C(lit.)
- 끓는 점
- 385.05°C (rough estimate)
- 알파
- 18.6 º (c=3, H2O)
- 밀도
- 1.3129 (rough estimate)
- 굴절률
- 33 ° (C=1, 1mol/L NaOH)
- 저장 조건
- 2-8°C
- 용해도
- 아세톤, DMSO(약간 용해됨), 에탄올, 에틸아세테이트, 메탄올(약간 용해됨, 가열)에 용해됨
- 산도 계수 (pKa)
- pK1:9.79;pK2:12.85 (25°C)
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 거의 흰색
- 수소이온지수(pH)
- 9.8
- optical activity
- [α]20/D +19±1°, c = 1% in H2O
- 수용성
- 녹는
- 최대 파장(λmax)
- 267 (pH 7);267 (pH 13)
- Merck
- 14,9397
- BRN
- 89285
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- IQFYYKKMVGJFEH-XLPZGREQSA-N
- LogP
- -0.930
- CAS 데이터베이스
- 50-89-5(CAS DataBase Reference)
- NIST
- Thymidine(50-89-5)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22-40-36/37/38-68 | ||
안전지침서 | 22-24/25-37/39-26-36/37/39 | ||
WGK 독일 | 3 | ||
RTECS 번호 | XP2071000 | ||
F 고인화성물질 | 10 | ||
TSCA | Yes | ||
HS 번호 | 29335990 | ||
기존화학 물질 | KE-09611 |
티미딘 C화학적 특성, 용도, 생산
개요
Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix. In cell biology it is used to synchronize the cells in G1/early S phase.화학적 성질
White needle crystal, soluble in methanol, ethanol, DMSO and other organic solvents.물리적 성질
Thymidine can exist in vitro conditions as a solid (as white crystals or as white crystalline powder). Under standard temperature and pressure, the stability of this compound is very high. As a part of DNA structure, thymidine occurs in living organisms (also in DNA viruses). Therefore, it is a non-toxic compound. In RNA, there is uridine instead of thymidine. Uridine is formed from the combination of uracil with ribose sugar. The key difference between thymine and thymidine is that thymine is a nucleobase, whereas thymidine is a nucleoside.용도
Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.정의
ChEBI: Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine.일반 설명
Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine.Safety Profile
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Crystallise -thymidine from ethyl acetate, MeOH/Et2O (m 188o) or H2O (as 2H2O m 189o). It is soluble in water and hot organic solvents. The picrate has m 230o (from EtOH).티미딘 준비 용품 및 원자재
원자재
준비 용품
티미딘 공급 업체
글로벌( 727)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 |
yunbiochem@126.com | China | 321 | 58 |
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 |
sales1@nuowei-chem.com | China | 1640 | 58 |
SHANGHAI NOVRIBO BIOTECH | 17821030819 |
June.Liu@Desano.com | China | 73 | 58 |
Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 |
Ryan@jiutian-bio.com | China | 7213 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
티미딘 관련 검색:
수용성전분 티민 지도부딘 티미딘
5-HYDROXYMETHYL-2'-DEOXYURIDINE
T-SUCCINATE5'-O-DMTR-THYMIDINE-SUCCINATE
5’-o-[bis(4-methoxyphenyl)phenylmethyl]-thymidi
THYMIDINE 5'-TRIPHOSPHATE SODIUM SALT,THYMIDINE-5'-TRIPHOSPHATE TETRASODIUM SALT,THYMIDINE-5'-TRIPHOSPHATE TRISODIUM SALT
Trifluridine
Thymidine-5'-monophosphate disodium salt
5’-o-(triphenylmethyl)-thymidi
DMT-dT Phosphoramidite
5-Methyluridine
3’-deoxy-thymidi
Deoxythymidine triphosphate
1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
3’-deoxy-3’-fluoro-thymidi
2’,3’-didehydro-3’-deoxy-thymidi