Ganirelix Acetate

Ganirelix Acetate 구조식 이미지
카스 번호:
123246-29-7
상품명:
Ganirelix Acetate
동의어(영문):
GANIRELIX;Ganirelixum;5-?dihydroxy-;3-?bis[[3-?(3;ganirelix Acetate;Ganirelix DiAcetate;Ganirelix Impurity 1;Ganirelix Acetate API;Ganirelix Acetate USP/EP/BP;4-?dihydroxyphenyl)?-?1-?oxo-?2-?propen-?1-?yl]?oxy]?-?4
CBNumber:
CB61370494
분자식:
C80H113ClN18O13
포뮬러 무게:
1570.34
MOL 파일:
123246-29-7.mol

Ganirelix Acetate 속성

시퀀스
Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu-Har(Et2)-Pro-DAla-NH2

안전

HS 번호 3504009000

Ganirelix Acetate C화학적 특성, 용도, 생산

Originator

Antagon,Organon

Therapeutic Function

LHRH antagonist

Clinical Use

Ganirelix acetate is an analog of GnRH with substitutions at residues 1, 2, 3, 6, 8, and 10. It is not a superagonist but, rather, is a synthetic decapeptide with high antagonist activity and the first GnRH antagonist to be marketed. It is approved for the suppression of LH surges in women who are undergoing ovarian hyperstimulation fertility treatment; LH surges normally promote ovulation. The goal of this drug is to significantly reduce the number of medication days necessary to suppress the LH surge, thereby maintaining eggs in the ovaries. In vitro fertilization (IVF) treatment cycles were historically initiated by the administration of leuprolide acetate to suppress the premature release of LH. This inhibits ovulation so that the eggs remain available for retrieval by a fertility specialist. For this purpose, leuprolide acetate usually is injected for as many as 26 days. Clinical studies have shown that ganirelix acetate can shut down the LH surge in only 5 days of treatment, that the suppression of LH is more pronounced than that of FSH, and that the shorter treatment time minimizes unpleasant side effects, such as hot flashes and headaches.

Ganirelix Acetate 준비 용품 및 원자재

원자재

준비 용품


Ganirelix Acetate 공급 업체

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