JACOLINE

JACOLINE 구조식 이미지
카스 번호:
480-76-2
상품명:
JACOLINE
동의어(영문):
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber:
CB61438381
분자식:
C18H27NO7
포뮬러 무게:
369.41
MOL 파일:
480-76-2.mol

JACOLINE 속성

녹는점
221°C
끓는 점
583.5±50.0 °C(Predicted)
밀도
1.36±0.1 g/cm3(Predicted)
산도 계수 (pKa)
12.40±0.60(Predicted)

안전

JACOLINE C화학적 특성, 용도, 생산

개요

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

용도

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

참고 문헌

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE 준비 용품 및 원자재

원자재

준비 용품


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