Pachymic acid

Pachymic acid C화학적 특성, 용도, 생산

용도

Pachymic Acid is a natural triterpene extract which suppresses invasiveness of pancreatic cancer cells through the downregulation of MMP-7.

Anticancer Research

Extracted from Poria cocos, pachymic acid (PA) is a tri-terpenoid (a lanostanetype), which is reported to have anticancerous properties. NCI-H460 and NCI-H23cells, the lung cancer cell lines, were studied for the effect of pachymic acid.Expression of a major UPR target gene-regulated protein, CHOP, was upregulatedresulting in cell apoptosis after PA treatment. It was discovered that ROS inhibitorsblocked the ER stress activation induced by PA. The results indicated that ROSproduction is also regulated by PA in lung cancer cells (Cheng et al. 2015; Jun et al.2015). As per the studies conducted on MIA PaCa-2 and PANC-1 cell lines,PA-induced apoptosis in pancreatic cancer cell resistant to gemcitabine wasdependent on in vivo and in vitro activation of ER stress. PA can be exploited for itsanticancer effects for treatment of pancreatic cancer resistant to chemotherapy(Cheng et al. 2015).

Pachymic acid 준비 용품 및 원자재

원자재

준비 용품

Pachymic acid 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	338	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253	jancyzheng@gcgreenpure.com	China	952	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58

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