5-Bromo-2-chloropyridine
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5-Bromo-2-chloropyridine 속성
- 녹는점
- 65-69 °C (lit.)
- 끓는 점
- 208.1±20.0 °C(Predicted)
- 밀도
- 1.7783 (rough estimate)
- 굴절률
- 1.5400 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 산도 계수 (pKa)
- -2.25±0.10(Predicted)
- 물리적 상태
- 결정질 분말 또는 결정
- 색상
- 회백색
- BRN
- 108887
- InChI
- InChI=1S/C5H3BrClN/c6-4-1-2-5(7)8-3-4/h1-3H
- InChIKey
- PEAOEIWYQVXZMB-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C(Br)C=C1
- CAS 데이터베이스
- 53939-30-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36-37/39-36/37/39 | ||
| WGK 독일 | 3 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | T | ||
| 위험 등급 | IRRITANT, IRRITANT-HARMFUL | ||
| HS 번호 | 29333990 |
5-Bromo-2-chloropyridine C화학적 특성, 용도, 생산
화학적 성질
Light yellow Cryst용도
5-Bromo-2-chloropyridine may be used in the preparation of following compounds:- Amino-2-chloropyridine via palladium-catalyzed amination.
- 5-Bromo-2-fluoropyridine via halogen-exchange reaction using anhydrous potassium fluoride.
- 2-Chloro-5-(2,5-dimethoxyphenyl)pyridine via Suzuki coupling with 2,5-dimethoxyphenylboronic acid.
Synthesis
6-Chloro-pyridin-3-ylamine was dissolved slowly with constant stirring in 48% HBr solution (50 mL) at r.t. and then the solution was cooled to -10 °C. A solution of sodium nitrite in cold water was added dropwise at -10 °C with constant stirring over 2 h, followed by a solution of copper (I) bromide in 48% HBr dropwise. The mixture was then stirred at r.t. until complete. The mixture was neutralized with sodium carbonate and extracted with ethyl acetate. The organic phase was washed with brine, dried over sodium sulfate, and concentrated. The residue was purified by column chromatography on silica gel (60-120 mesh) eluting with 1% ethyl acetate/petroleum ether to afford 5- bromo-2-chloropyridine.
5-Bromo-2-chloropyridine 준비 용품 및 원자재
원자재
3-Bromo-4-chloropyridine
5-BROMO-1-METHYL-2(1H)-PYRIDINONE
5-Bromo-2-chloropyridine N-oxide
3-Bromo-2-chloropyridine
3-BROMOPYRIDINE-N-OXIDE
준비 용품
5-Bromo-2-chloropyridine 공급 업체
글로벌( 586)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 |
Lingzhiyue@aliyun.com | China | 3138 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com |
jocelynpan@zjarts.com | CHINA | 993 | 58 |
5-Bromo-2-chloropyridine 관련 검색:
2-클로로-5-클로로메틸피리딘 클로피돌 클로로디플루오르메탄 브롬 2-클로로피리딘
2-Chloro-3-cyanopyridine
2-Chloro-5-fluoropyridine
1-Hexadecylpyridinium bromide
5-Amino-2-chloropyridine
2-chloro-5-cyanopyridine
3-Bromo-6-chloro-2-methylpyridine
6-Chloro-2-methyl-3-nitropyridine
2-Chloro-5-hydroxypyridine
2-CHLORO-5-METHOXYPYRIDINE
2-Chloro-5-nitropyridine
2-Chloro-5-iodopyridine
5-Bromo-2-chlorobenzoic acid
pyridinium Chlorochromate