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P501
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NFPA 704
1
2
0
디글리시딜1,2-시클로헥산디카르복실레이트 C화학적 특성, 용도, 생산
화학적 성질
Colorless or light yellow liquid
용도
It is used in epoxy-based industrial coatings and paints.
일반 설명
Clear yellow viscous liquid.
공기와 물의 반응
Insoluble in water.
반응 프로필
Diglycidyl 1,2-cyclohexanedicarboxylate is incompatible with strong oxidizers, acids and alkalis.
화재위험
Diglycidyl 1,2-cyclohexanedicarboxylate is combustible.
Carcinogenicity
HPADGE was tested in vitro for
gene mutation effects in S. typhimurium at concentrations up
to 231 mg/mL and was positive in strains TA100 and
TA1535. HPADGE has also been reported as positive
in the mouse lymphoma assay. Negative results were
found in the BALB/3T3 fibroblast transformation assay
at concentrations up to 30 mg/mL. In vivo,
HPADGE administered orally in a single dose of 1250,
2500, or 5000 mg/kg to Chinese hamsters produced a statistically
significant increase in SCEs in bone marrow cells
at the two higher dose levels. Mice given a single oral
dose of 500 or 1000 mg/kg had a statistically significant
increase in the frequency of micronucleated polychromatic
erythrocytes compared to negative controls.