ChemicalBook >제품 카탈로그 >제약 중간체>벌크 의약품 중간체>tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 구조식 이미지

카스 번호:: 571188-59-5

상품명:: tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

동의어(영문):: 1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE;OTAVA-BB;4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester;OTAVA-BB 1207229;1-Boc-4-(6-amino-3-pyridyl)piperazine;tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate;POB02;Ribociclib-2;PALBOCICLIB4;Palbociclib-11

CBNumber:: CB62464781

분자식:: C14H22N4O2

포뮬러 무게:: 278.35

MOL 파일:: 571188-59-5.mol

속성

안전

용도

공급 업체 560

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 속성

녹는점: 130-132℃

끓는 점: 454.1±45.0 °C(Predicted)

밀도: 1.182

증기압: 0-0Pa at 20-25℃

저장 조건: Keep in dark place,Inert atmosphere,Room temperature

용해도: DMSO(약간 용해됨), 메탄올(매우 소량)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 7.36±0.26(Predicted)

색상: 진한 노란색

감도: Air Sensitive

InChI: InChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)

InChIKey: RMULRXHUNOVPEI-UHFFFAOYSA-N

SMILES: N1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1

LogP: 1.6-1.8 at 35℃ and pH7-9

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2933599590

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405	밀봉하여 저장하시오.

NFPA 704

	0
2		0

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate C화학적 특성, 용도, 생산

용도

4-(6-Amino-3-pyridyl)-1-Boc-piperazine (tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate) is used as an organic chemical synthesis intermediate.

제조 방법

4- (6-Nitro-pyridin-3-yl)-piperazine-1 -carboxylic acid ie f-butyl ester and Pd/C in ethanol is stirred with an H2 balloon for 3 h. The product tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is obtained through purification.

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 준비 용품 및 원자재

원자재

1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE tert-Butyl 1-piperazinecarboxylate 2-Amino-5-iodopyridine

준비 용품

Pyrido[2,3-d]pyriMidine-6-carboxylic acid, 8-cyclopentyl-2-[[5-[4-[(1,1-diMethylethoxy)carbonyl]-1-piperazinyl]-2-pyridinyl]aMino]-7,8-dihydro-5-Methyl-7-oxo-, ethyl ester

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 공급 업체

글로벌( 560)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou Qiwei Pharmatech Co.,Ltd	13282840061	mw@qwpharmatech.com	China	109	58
ChemExpress	+86-021-58950125	info@chemexpress.com	China	557	58
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.	+86-0531-69954981 +8615666777973	dwyane.wang@boyuanpharm.com	China	211	58
Shanghai Joiny Pharmaceutical Co.,LTD	+8613681955282	gyd@joiny-pharma.com	China	228	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 관련 검색:

메틸 아이오다이드 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 1-N-BOC-4-BROMOPIPERIDINE Copper(II) chloride dihydrate sacubitril 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER PD 0332991 HCl 1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester LEE011 (succinate) 2-Chloro-7-cyclopentyl-N,N-dimethyl-H-pyrrolo[2,3-d]pyrimidine-6-carboxamide 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]-2-nitro- LEE011 (hydrochloride) 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Cholan-24-oic acid,6-ethyl-3-hydroxy-7-oxo-,(3α,5β,6β)- Palbociclib tert-Butyl 3-allyl-4-oxopyrrolidine-1-carboxylate