ChemicalBook >제품 카탈로그 >4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 구조식 이미지

카스 번호:: 917392-54-2

상품명:: 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

동의어(영문):: NILOTINIB EP IMPURITY G;917392-54-2;Nilotinib Impurity 12 (Nilotinib EP Impurity G);Nilotinib Hydrochloride Monohydrate EP Impurity G; 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa...;Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate;4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester;4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

CBNumber:: CB62490045

분자식:: C18H16N4O2

포뮬러 무게:: 320.35

MOL 파일:: 917392-54-2.mol

속성

안전

용도

공급 업체 111

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 속성

녹는점: 148 - 150°C

끓는 점: 538.6±60.0 °C(Predicted)

밀도: 1.258

저장 조건: 2-8°C

용해도: 클로로포름 (약간 용해됨), DMSO (약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 2.70±0.12(Predicted)

색상: 옅은 노란색에서 밝은 베이지색까지

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2916399090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고	P264, P270, P301+P312, P330, P501
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester C화학적 특성, 용도, 생산

용도

Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 준비 용품 및 원자재

원자재

Methyl 3-amino-4-methylbenzoate 3-[(aMinoiMinoMethyl)aMino]-4-Methylbenzoic acid Methyl ester Mononitrate 4-(3-Pyridyl)-2-chloropyrimidine Methyl 3-bromo-4-methylbenzoate METHYL 3-IODO-4-METHYLBENZOATE 3-Pyridylboronic acid 4-(Pyridin-3-yl)pyrimidin-2-amine 3-아세틸피리딘 메틸알콜

준비 용품

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 닐로티닙

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 공급 업체

글로벌( 111)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1320	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20356	58

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 관련 검색:

NILOTINIB IMPURITY 11 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]- 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- Methyl 3-amino-4-methylbenzoate Nilotinib Impurity 10 Nilotinib N-Oxide Nilotinib Impurity 7 Nilotinib genotoxic impurity 3 Nilotinib Impurity 1 Nilotinib Impurity 20 3-Amino-4-methylbenzoic acid Nilotinib Impurity 28 Nilotinib impurity 3