CMPF

CMPF 구조식 이미지
카스 번호:
86879-39-2
상품명:
CMPF
동의어(영문):
CMPF;Furanic acid;CMPF Exclusive;Propylfuranoic acid;3-carboxy-4-methyl-5-propyl-2-furanpropionic acid;3-Carboxy-4-methyl-5-propylfuran 2-propanoic acid;3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPANOIC ACID;2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-;CMPF, 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid;3-[(3-Carboxy-4-methyl-5-propylfuran)-2-yl]propionic acid
CBNumber:
CB6250601
분자식:
C12H16O5
포뮬러 무게:
240.25
MOL 파일:
86879-39-2.mol
MSDS 파일:
SDS

CMPF 속성

녹는점
>174°C (Subl.)
끓는 점
404.0±45.0 °C(Predicted)
밀도
1.236±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
클로로포름(아주 약간 용해됨), DMSO(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.38±0.10(Predicted)
색상
흰색에서 옅은 베이지까지

안전

RTECS 번호 LU5240766

CMPF C화학적 특성, 용도, 생산

용도

CMPF is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.

정의

ChEBI: A furoic acid that is furan-3-carboxylic acid substituted by a methyl group at position 4, a propyl group at position 5 and a 2-carboxyethyl group at position 2. It is a potent uremic toxin that has been found to accumulate in human serum of patients with hronic kidney diseases.

일반 설명

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids, is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions. It is mostly reported to be accumulated in chronic kidney disease (CKD) patients. Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin. It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.

CMPF 준비 용품 및 원자재

원자재

준비 용품


CMPF 공급 업체

글로벌( 28)공급 업체
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ATK CHEMICAL COMPANY LIMITED
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SyncoZymes (Shanghai) Co., Ltd.,
+86-021-68187180-811 +86-13681683526
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Aladdin Scientific
+1-833-552-7181
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Syncozymes (Shanghai) Co.,Ltd. 021-68187180-819 13681683526
lchen@syncozymes.com China 186 55
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719
root@zhongyitai.com China 1976 58
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396
sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
greensnown@163.com China 9911 50
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
info@SuperLan-chem.com China 9374 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58

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