Chinese English Japanese Germany Korea


에리트리톨 구조식 이미지
카스 번호:
Paycite;Phycite;Erythrit;Phycitol;Phytcite;tetritol;ERYTHRITE;erythrine;Erithrite;red cobalt
포뮬러 무게:
MOL 파일:

에리트리톨 속성

118-120 °C(lit.)
끓는 점
329-331 °C(lit.)
1,451 g/cm3
1.4502 (estimate)
저장 조건
H2O: 0.1 g/mL, clear to almost clear, colorless
산도 계수 (pKa)
13.9(at 25℃)
물리적 상태
Crystalline Powder or Crystals
White to off-white
Stable. Incompatible with strong oxidizing agents.
CAS 데이터베이스
149-32-6(CAS DataBase Reference)
Erythrol (149-32-6)


위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36
WGK 독일 3
RTECS 번호 KF2000000
F 고인화성물질 3-10
HS 번호 29054910
독성 LD50 in male, female rats (g/kg): 6.6, 9.6 i.v.; >16, >16 s.c.; 13.1, 13.5 orally (Munro)
기존화학 물질 KE-13121

에리트리톨 MSDS


에리트리톨 C화학적 특성, 용도, 생산


성상 : 결정, 색상 : 백색, 녹는점/어는점 : 121.5 ℃, 초기 끓는점과 끓는점 범위 : 329~331 ℃, 증기압 : 0.0000237 ㎜Hg (25℃(EXP)), 용해도 : 610000 ㎎/ℓ (22℃(EXP)), 비중 : 1.451 (20℃), n-옥탄올/물분배계수 (Kow) : -2.29 (EXP)(Log Kow).


에리스리톨은 내열성이 뛰어나 200℃에서 1시간 동안 가열하여도 분해되지 않을 뿐만 아니라, 흡습성도 낮아서 결정을 쉽게 형성하는 장점을 가지고 있다.
감미도는 설탕의 70∼80%의 감미를 가지고 있고 용해시에 흡열작용이 매우 강하여 청량감이 뛰어나다. 또한 장점 중에 대표적인 것은 저칼로리 식품이라는 것인데 다른 감미료와 달리 체내에서 에너지원으로 이용되지 않고 소변으로 대부분 배출된다. 그 밖에 충치균 등에 의해 이용되지 않기 때문에 충치를 일으키지도 않는다.


식첨용 용도로는 향미증강제, 감미료, 습윤제 등에 사용된다.

화학적 성질

white crystals or powder

화학적 성질

Erythritol (meso-erythritol, meso-1,2,3,4-Tetrahydroxybutan) has been known for a long time. Its potential use as a bulk sweetener was, however, recognized rather late.
Erythritol is a natural constituent of several foods and beverages in levels sometimes exceeding 1 g/kg. Its solubility in water is approximately 370 g/L at room temperature and increases with increasing temperature. Erythritol melts at 121 C and is stable up to more than 160 C and in a pH range from 2 to 10. Depending on the concentration used, erythritol is approximately 60 % as sweet as sucrose. It is noncariogenic and not metabolized in the human body which means that it is more or less calorie-free.
In the European Union, erythritol is approved as E 968 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.

화학적 성질

Erythritol is a sugar alcohol (polyol) that occurs as a white or almost white powder or granular or crystalline substance. It is pleasant tasting with a mild sweetness approximately 60–70% that of sucrose. It also has a high negative heat of solution that provides a strong cooling effect.


Erythritol is a sweetener (polyol) manufactured by fermentation of glucose, the glucose-rich substrate being obtained by the enzymatic hydrolysis of starch. it is 60–70% as sweet as sugar, has excellent heat and acid stability, a high digestive tolerance, and a caloric value of 0.2 kcal/g. it is the only polyol produced by fermentation. it can be used as a sugar replacement in confectioneries, beverages, and desserts.


Non-nutritive sweetener in beverages.


non-cariogenic, low-calorie (0.4 kcal/g) sweetener


ChEBI: The meso-diastereomer of butane-1,2,3,4-tetrol.

생산 방법

Erythritol is a starch-derived product. The starch is enzymatically hydrolyzed into glucose which is turned into erythritol via a fermentation process, using osmophilic yeasts or fungi (e.g. Moniliella pollinis, or Trichosporonoides megachiliensis).

생명 공학 생산

The synthesis of erythritol is rather difficult. One of the possibilities is the catalytic reduction of tartaric acid with Raney nickel, which does, however, also produce threitol, a diastereomere of erythritol that requires separation of both. Threitol may be isomerized which increases the yields of erythritol. Another chemical synthesis starts from butane-2-diol-1.4 which is reacted with chlorine in aqueous alkali to yield erythritol-2-chlorohydrin and can be hydrolyzed with sodium carbonate solution. Synthesis from dialdehyde starch in the presence of a nickel catalyst at high temperatures is also possible.
Owing to the special physiological properties of erythritol, commercial interest increased with the discovery of an increasing number of microorganisms able to produce this substance. Today, the commercial production of erythritol is apparently only based on fermentation.
Erythrytitol fermentations mostly use osmophilic yeasts. Based on regulatory submissions for commercial production, T. megachiliensis, M. pollinis, and Y. lipolytica are used. It is also claimed that P. tsukubaensis and Aureobasidium sp. are used for commercial production.
Erythritol-producing microorganisms often produce other polyols such as ribitol. Nevertheless, some strains had a rather high yield of erythritol. A two-step fermentation of C. magnoliae on 400 g/L glucose resulted in a 41 % conversion rate and a productivity of 2.8 g/Lh. M. pollinis cultivated on glucose and several nitrogen sources yielded erythritol concentrations up to 175 g/L with a conversion rate of 43 %. Oxygen limitation resulted in ethanol formation, and nitrogen limitation in strong foaming. A mutant gave even better yields. Aerobically on glucose cultured P. tsukubaensis KN 75 produced 245 g/L of erythritol with an especially high yield of 61 %. The productivity was 2.86 g/Lh. Scale-up from 7-L laboratory fermenter to 50,000-L industrial scale resulted in productivities similar to the laboratory value.

Pharmaceutical Applications

Erythritol is a naturally occurring noncariogenic excipient used in a variety of pharmaceutical preparations, including in solid dosage forms as a tablet filler, and in coatings. It has also been investigated for use in dry powder inhalers.It is also used in sugar-free lozenges,and medicated chewing gum.
Erythritol can also be used as a diluent in wet granulation in combination with moisture-sensitive drugs. In buccal applications, such as medicated chewing gums, it is used because of its high negative heat of solution which provides a strong cooling effect.
Erythritol is also used as a noncaloric sweetener in syrups; it is used to provide sensorial profile-modifying properties with intense sweeteners; and it is also used to mask unwanted aftertastes.
Erythritol is also used as a noncariogenic sweetener in toothpastes and mouthwash solutions.


Erythritol is used in oral pharmaceutical formulations, confectionery, and food products. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material. However, there has been a case report of urticaria caused by erythritol.
The low molecular weight of erythritol allows more than 90% of the ingested molecules to be rapidly absorbed from the small intestine; it is not metabolized and is excreted unchanged in the urine. Erythritol has a low caloric value (0.8 kJ/g). The WHO has set an acceptable daily intake of ‘not specified’ for erythritol.
Erythritol is noncariogenic; preliminary studies suggest that it may inhibit the formation of dental plaque.
In general, erythritol is well-tolerated; furthermore, excessive consumption does not cause laxative effects. There is no significant increase in the blood glucose level after oral intake, and glycemic response is very low, making erythritol suitable for diabetics.
LD50 (mouse, IP): 8–9 g/kg
LD50 (rat, IV): 6.6 g/kg
LD50 (rat, oral): >13 g/kg


Erythritol has very good thermal and chemical stability. It is nonhygroscopic, and at 25°C does not significantly absorb additional water up to a relative humidity (RH) of more than 80%. Erythritol resists decomposition both in acidic and alkaline media and remains stable for prolonged periods at pH 2–10.(10) When stored for up to 4 years in ambient conditions (20°C, 50% RH) erythritol has been shown to be stable.

Purification Methods

meso-Erythritol crystallises from distilled water or absolute EtOH and is dried at 60o in a vacuum oven. It sublimes at 110o in a high vacuum. It is optically inactive. [Jeans & Hudson J Org Chem 20 1565 1955, IR: Kuhn Anal Chem 22 276 1950, Beilstein 1 IV 2807.]

비 호환성

Erythritol is incompatible with strong oxidizing agents and strong bases.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe.

에리트리톨 준비 용품 및 원자재


준비 용품

에리트리톨 공급 업체

글로벌( 340)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 2759 55
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23040 58
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
02569916489 CHINA 150 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22623 55
Hebei Chishuo Biotechnology Co., Ltd.
13292891350 +86 311 66567340 CHINA 969 58
career henan chemical co
+86-371-86658258 CHINA 30033 58
Zhengzhou Yuanli Biological Technology Co., Ltd
0086-371-67897895 CHINA 136 58
+86 18953170293
+86 0531-67809011 CHINA 2995 58
+86 532 83657313 CHINA 231 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28230 58

Copyright 2019 © ChemicalBook. All rights reserved