라노스테롤
|
|
라노스테롤 속성
- 녹는점
- 137 °C
- 알파
- D20 +62.0° (chloroform)
- 끓는 점
- 482.1°C (rough estimate)
- 밀도
- 0.9600 (rough estimate)
- 굴절률
- 1.4910 (estimate)
- 저장 조건
- -20°C
- 용해도
- 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
- 산도 계수 (pKa)
- 15.16±0.70(Predicted)
- 물리적 상태
- 가루
- 색상
- 하얀색
- 냄새
- 100.00?%. 온화한
- Merck
- 5360
- InChIKey
- CAHGCLMLTWQZNJ-BQNIITSRSA-N
- LogP
- 10.521 (est)
- CAS 데이터베이스
- 79-63-0(CAS DataBase Reference)
안전
| WGK 독일 | 1 | ||
|---|---|---|---|
| RTECS 번호 | OE3360000 |
라노스테롤 C화학적 특성, 용도, 생산
개요
Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts. Similarly, certain fungicides act by blocking lanosterol processing by fungi.용도
Lanosterol has been used:- as a standard in HPLC for the quantification in testis samples
- in S-adenosyl-L-methionine:Δ24-sterol-C-methyltransferase (SMT) assay
- to treat wild-type cells growing in rich medium to know its effects on Sre1 protein
정의
ChEBI: A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.일반 설명
Lanosterol, an amphipathic molecule, that is produced by?lanosterol?synthase (LSS). It is enriched in the lens.Purification Methods
If very impure, then it should be acetylated, converted to the dibromide acetate [crystallised from EtOAc with slow cooling, m 168-170o, [] D +214o (CHCl3)], de-brominated with Zn dust to give the acetate (below) which is recrystallised from 3-4 parts of Me2CO/MeOH (4:1) and hydrolysed as for stigmasterol (below). Recrystallise it from anhydrous MeOH. Dry it in vacuo over P2O5 for 3hours at 90o. The purity is checked by proton magnetic resonance. The acetate crystallises from MeOH with m 131-133o and [ ] 25D +62o (c 1,CHCl3). [Block & Urech Biochemical Preparations 6 32 1958. van Tamelen et al. J Am Chem Soc 104 6479, 6480 1982, Beilstein 6 III 2880, 6 IV 4188.]라노스테롤 준비 용품 및 원자재
원자재
준비 용품
라노스테롤 공급 업체
글로벌( 209)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
라노스테롤 관련 검색:
사이클로헥실에텐 데카디엔 트랜스-5-데켄-1-OL
CIS-2,5-DIMETHYL-3-HEXENE
VINYLCYCLOPENTANE
LANOSTEROL
C10-30 CHOLESTEROL/LANOSTEROL ESTERS
DIHYDROLANOSTEROL
CYCLOARTENYL FERULATE
p-menth-3-ene
1,10-UNDECADIENE
2,2,4,6,6-PENTAMETHYL-3-HEPTENE
2-(3-cyclohexenyl)ethanol
3,5-DIMETHYL-3-HEPTENE
1,13-TETRADECADIENE
LANOSTEROL(3/3-HYDROXY-8,24-IANOSTADIENE)
lanosteryl acetate
1-CYCLOHEXYLCYCLOHEXENE