Cefodizime

Cefodizime 구조식 이미지
카스 번호:
69739-16-8
상품명:
Cefodizime
동의어(영문):
FIR-221;Estrofan;Cefodizim;Cefodizme;CEFODIZIME;Cefodizime,CDZM;CefodizMe SodiuM;Sodium cefodizime;CEFODIZIME FREE ACID;Cefodizime USP/EP/BP
CBNumber:
CB6299020
분자식:
C20H20N6O7S4
포뮬러 무게:
584.67
MOL 파일:
69739-16-8.mol

Cefodizime 속성

녹는점
>170°C (dec.)
알파
D25 -55.9°
밀도
1.86±0.1 g/cm3(Predicted)
저장 조건
-20°C Freezer
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨, 가열)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
pK1 2.85; pK2 3.37; pK3 4.18(at 25℃)
색상
흰색에서 황백색까지
CAS 데이터베이스
69739-16-8(CAS DataBase Reference)

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38-42/43
안전지침서 22-26-36/37/39

Cefodizime C화학적 특성, 용도, 생산

화학적 성질

Cefodizime Sodium is a white to light yellowish white crystalline powder. It has no odor or a slightly peculiar odor and has a bitter taste. It is highly soluble in water (around 270g/L) but only sparingly soluble in ethanol or ether.

제조 방법

The synthesis of cefodizime involved the following steps:
Dissolve 6.1g of (2-mercapto-4-methylthiazol-5-yl) acetic acid in water and adjust the pH to 6.5 by adding 2 mol/L sodium hydroxide.
Heat the solution to 70°C and then add a solution of 12g of cefotaxime in 75ml of water with stirring.
Keep stirring the mixture at 70°C for 3 hours while maintaining the pH at 6.5 by adding 2 mol/L sodium hydroxide.
Cool the mixture to room temperature and acidify it to pH 2.8.
Filter the resulting precipitate and wash it with water.
Dry the precipitate under vacuum and in the presence of phosphorus pentoxide.
As a result, 10g of cefodizime is obtained.
Cefodizime, an aminothiazolylcephalosporin. V. Synthesis and structure-activity relationships in the cefodizime series. DOI: 10.7164/antibiotics.40.29

정의

ChEBI: Cefodizime is a cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It has a role as an antibacterial drug and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a cephalosporin, a member of 1,3-thiazoles and an oxime O-ether.

Cefodizime 준비 용품 및 원자재

원자재

준비 용품


Cefodizime 공급 업체

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