AZD2098
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AZD2098 속성
- 녹는점
- 185-186°C
- 끓는 점
- 489.3±55.0 °C(Predicted)
- 밀도
- 1.569±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO에 용해됨(>25 mg/ml)
- 산도 계수 (pKa)
- 5.56±0.40(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 안정성
- 공급된 대로 1년 동안 안정적입니다. DMSO 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.
안전
AZD2098 C화학적 특성, 용도, 생산
Biochem/physiol Actions
AZD-2098 is an orally active, potent and selective CCR4 antagonist (pIC50 = 7.8/8.0/8.0/7.6 against CCL22 binding to human/mouse/rat/dog CCR4; inactive toward CXCR1/2 & CCR1/2b/5/7/8 at 10 μM) with little or no activity toward a panel of ～120 receptors/enzymes. AZD-2098 effectively inhibits chemokine-induced cellular responses in vitro (pIC50 = 7.5 against CCL22-induced calcium influx in hCCR4-expressing CHO cells; pIC50 = 6.3 against CCL17- or CCL22-induced chemotaxis of primary human Th2 cells) and exhibits efficacy against antigen-induced inflammatory response among ovalbumin-sensitized rats in vivo (Emax = 7.5 μmol/kg p.o.; 1 h before and every 12 h after antigen challenge).AZD2098 준비 용품 및 원자재
원자재
준비 용품
AZD2098 공급 업체
글로벌( 52)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 |
sales@meilune.com | China | 4647 | 58 |
| MedChemexpress LLC | 021-58955995 |
sales@medchemexpress.cn | United States | 4863 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 |
China | 4121 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
AZD2098 관련 검색:
DO264
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