아세토히드록삼 산
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아세토히드록삼 산 속성
- 녹는점
- 88-90 °C (lit.)
- 끓는 점
- 133.7°C (rough estimate)
- 밀도
- 1.2269 (rough estimate)
- 굴절률
- 1.4264 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 결정질 고체
- 산도 계수 (pKa)
- 8.70(at 25℃)
- 색상
- 흰색에서 연한 노란색
- 수용성
- 물에 용해됩니다.
- 감도
- Hygroscopic
- Merck
- 14,63
- BRN
- 1739019
- 안정성
- 수분 및 온도에 민감함
- InChIKey
- RRUDCFGSUDOHDG-UHFFFAOYSA-N
- CAS 데이터베이스
- 546-88-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T | ||
---|---|---|---|
위험 카페고리 넘버 | 61-40 | ||
안전지침서 | 53-45-36/37/39-22 | ||
유엔번호(UN No.) | 3263 | ||
WGK 독일 | 3 | ||
RTECS 번호 | AK8157000 | ||
위험 참고 사항 | Toxic | ||
포장분류 | II | ||
HS 번호 | 29225090 | ||
유해 물질 데이터 | 546-88-3(Hazardous Substances Data) | ||
독성 | mmo-sat 160 mmol/plate JOPHDQ 3,557,80 | ||
기존화학 물질 | KE-00066 |
아세토히드록삼 산 C화학적 특성, 용도, 생산
개요
Acetohydroxamic acid is a potent, non-competitive and irreversible inhibitor of bacterial urease (Ki≈lO-7M). This enzyme, which is widely distributed in plants and bacteria, but not in mammalian cells, catalyzes the decomposition of urea to ammonia. Elevated urinary ammonia levels can reduce the antibacterial effectiveness of a number of agents. Thus, acetohydroxamic acid is useful as adjunctive therapy to decrease urinary ammonia and alkalinity in patients with chronic urea-splitting urinary infection. Such infections are a leading cause of recurring complications and death in paraplegics.화학적 성질
White Crystalline Solid용도
Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.Acetohydroxamic acid was used:
to study the mechanism of complexation of iron (III) with acetohydroxamic acid.
to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni.
in urease inhibition studies.
for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.
Used in urease inhibition studies and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.
일반 설명
Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.부작용
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have:
pounding heartbeats or fluttering in your chest;
signs of a blood clot in your leg --pain, swelling, warmth, or redness in one or both legs;
signs of a red blood cell disorder --pale or yellowed skin, dark colored urine, fever, confusion or weakness.
Common side effects may include:
headache during the first 2 days of treatment;
skin rash, warmth, tingling or redness (especially if you drink alcohol while taking acetohydroxamic acid);
upset stomach, nausea, loss of appetite;
depressed mood;
anxiety, tremors, nervousness;
hair loss.
Safety Profile
Moderately toxic by intraperitonealroute. An experimental teratogen. Other experimentalreproductive effects. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.아세토히드록삼 산 준비 용품 및 원자재
원자재
준비 용품
아세토히드록삼 산 공급 업체
글로벌( 509)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86-13288715578 +86-13231137666 |
sales@hbmojin.com | China | 12409 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5960 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 14770 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21703 | 55 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29919 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |