아세토히드록삼 산

아세토히드록삼 산
아세토히드록삼 산 구조식 이미지
카스 번호:
546-88-3
한글명:
아세토히드록삼 산
동의어(한글):
아세토하이드록사믹산;아세토히드록삼산;아세토히드록삼산(ACETOHYDROXAMICACID)
상품명:
Acetohydroxamic acid
동의어(영문):
AHA;N-HYDROXYACETAMIDE;Acetylhydroxamic acid;Acetomenadione;Acetylhydroxylamine;NSC 5073;Lithostat;NSC 176136;NSC 408425;yangwosuan
CBNumber:
CB6395344
분자식:
C2H5NO2
포뮬러 무게:
75.07
MOL 파일:
546-88-3.mol
MSDS 파일:
SDS

아세토히드록삼 산 속성

녹는점
88-90 °C (lit.)
끓는 점
133.7°C (rough estimate)
밀도
1.2269 (rough estimate)
굴절률
1.4264 (estimate)
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
용해도
메탄올(약간 용해됨), 물(약간 용해됨)
물리적 상태
결정질 고체
산도 계수 (pKa)
8.70(at 25℃)
색상
흰색에서 연한 노란색
수용성
물에 용해됩니다.
감도
Hygroscopic
Merck
14,63
BRN
1739019
안정성
수분 및 온도에 민감함
InChIKey
RRUDCFGSUDOHDG-UHFFFAOYSA-N
CAS 데이터베이스
546-88-3(CAS DataBase Reference)
NIST
Acetamide,N-hydroxy(546-88-3)
EPA
Acetohydroxamic acid (546-88-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 61-40
안전지침서 53-45-36/37/39-22
유엔번호(UN No.) 3263
WGK 독일 3
RTECS 번호 AK8157000
위험 참고 사항 Toxic
포장분류 II
HS 번호 29225090
유해 물질 데이터 546-88-3(Hazardous Substances Data)
독성 mmo-sat 160 mmol/plate JOPHDQ 3,557,80
기존화학 물질 KE-00066
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H360 태아 또는 생식능력에 손상을 일으킬 수 있음 생식독성 물질 구분 1A, 1B 위험 GHS hazard pictograms
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
NFPA 704
1
1 0

아세토히드록삼 산 MSDS


Acetohydroxamic acid

아세토히드록삼 산 C화학적 특성, 용도, 생산

개요

Acetohydroxamic acid is a potent, non-competitive and irreversible inhibitor of bacterial urease (Ki≈lO-7M). This enzyme, which is widely distributed in plants and bacteria, but not in mammalian cells, catalyzes the decomposition of urea to ammonia. Elevated urinary ammonia levels can reduce the antibacterial effectiveness of a number of agents. Thus, acetohydroxamic acid is useful as adjunctive therapy to decrease urinary ammonia and alkalinity in patients with chronic urea-splitting urinary infection. Such infections are a leading cause of recurring complications and death in paraplegics.

화학적 성질

White Crystalline Solid

용도

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.
Acetohydroxamic acid was used:
to study the mechanism of complexation of iron (III) with acetohydroxamic acid.
to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni.
in urease inhibition studies.
for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.
Used in urease inhibition studies and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.

일반 설명

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.

부작용

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
pounding heartbeats or fluttering in your chest;
signs of a blood clot in your leg --pain, swelling, warmth, or redness in one or both legs;
signs of a red blood cell disorder --pale or yellowed skin, dark colored urine, fever, confusion or weakness.
Common side effects may include:
headache during the first 2 days of treatment;
skin rash, warmth, tingling or redness (especially if you drink alcohol while taking acetohydroxamic acid);
upset stomach, nausea, loss of appetite;
depressed mood;
anxiety, tremors, nervousness;
hair loss.

Safety Profile

Moderately toxic by intraperitonealroute. An experimental teratogen. Other experimentalreproductive effects. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.

아세토히드록삼 산 준비 용품 및 원자재

원자재

준비 용품


아세토히드록삼 산 공급 업체

글로벌( 509)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666
sales@hbmojin.com China 12409 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5960 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 14770 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21703 55
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967
kaia@neputrading.com China 1011 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29919 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2931 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282
alice@crovellbio.com China 8823 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953
info@konochemical.com China 2995 58

아세토히드록삼 산 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved