SCUTELLAREIN

SCUTELLAREIN 구조식 이미지
카스 번호:
529-53-3
상품명:
SCUTELLAREIN
동의어(영문):
SCUTELLAREIN;Scutillarein;Scutellartln;isocarthamidin;High baicalein;6-HYDROXYAPIGENIN;SCUTELLAREIN WITH HPLC;SCUTELLAREIN, 98.0% BY HPLC;5,6,7,4'-TETRAHYDROXYFLAVONE;4',5,6,7-TETRAHYDROXYFLAVONE
CBNumber:
CB6402688
분자식:
C15H10O6
포뮬러 무게:
286.24
MOL 파일:
529-53-3.mol
MSDS 파일:
SDS

SCUTELLAREIN 속성

녹는점
330°C
끓는 점
642.9±55.0 °C(Predicted)
밀도
1.654±0.06 g/cm3(Predicted)
저장 조건
Sealed in dry,2-8°C
용해도
DMSO: 가용성 1mg/mL, 투명, 녹황색
산도 계수 (pKa)
6.34±0.40(Predicted)
물리적 상태
가루
색상
노란색
InChIKey
JVXZRQGOGOXCEC-UHFFFAOYSA-N
LogP
2.540 (est)

안전

안전지침서 24/25
WGK 독일 3
HS 번호 29329990

SCUTELLAREIN C화학적 특성, 용도, 생산

개요

Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities. It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 μg/ml. Scutellarein inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively). It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-α induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 μM. In vivo, scutellarein (0.5 μg/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.

화학적 성질

Yellow solid

용도

Scutellarein is a flavonoid that can be found in Scutellaria lateriflora. Scutellarein is a hydrolysis product of Scutellarein (S201900), its glucuronide conjugated analogue.

정의

ChEBI: Flavone substituted with hydroxy groups at C-4', -5, -6 and -7.

SCUTELLAREIN 준비 용품 및 원자재

원자재

준비 용품


SCUTELLAREIN 공급 업체

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