2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
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2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide 속성
- 녹는점
- 229-232°C
- 끓는 점
- 410.8±45.0 °C(Predicted)
- 밀도
- 1.424±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMSO(최대 30mg/ml) 또는 에탄올(가온 시 최대 5mg/ml)에 용해됩니다.
- 산도 계수 (pKa)
- 5.20±0.50(Predicted)
- 색상
- 하얀색
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
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| 위험 카페고리 넘버 | 22 | ||
| HS 번호 | 2926900005 | ||
| 독성 | mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),United States Patent Document. Vol. #5494911, |
| 그림문자(GHS): |
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| 신호 어: | Danger | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide C화학적 특성, 용도, 생산
개요
Teriflunomide (Aubagio®), also known as A77 1726, is an immunosupressant marketed by Sanofi for the teatment of multiple sclerosis (MS). Teriflunomide is the active metabolite of leflunomide, used for treatment of patients diagnosed with rheumatoid arthritis, and therefore simultaneously can be used as a treatment for rheumatoid arthritis.Teriflunomide acts as an inhibitor of the mitochondrial enzyme dihydrorotate dehydrogenase, inhibiting pyrimidine formation, and resulting in reduced B and T cell proliferation.화학적 성질
White Solid용도
The active metabolite of Leflunomide, 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide can be used as a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis.2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide 준비 용품 및 원자재
원자재
준비 용품
2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide 공급 업체
글로벌( 162)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 |
mcbio_sales@163.com | China | 2255 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29271 | 58 |
2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide 관련 검색:
BESTATIN HYDROCHLORIDE
Palmitoylethanolamide
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
Acetylcholine
Glatiramer acetate
Histamine
DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
Pimecrolimus
Bortezomib
SB 415286
Anacetrapib
Lacidipine
Afatinib
Olaparib
2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
CROTONAMIDE
Teriflunomide-d4
2-CYANO-N-P-TOLYL-ACETAMIDE