UPCDC30245
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UPCDC30245 속성
- 끓는 점
- 647.6±55.0 °C(Predicted)
- 밀도
- 1.20±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 산도 계수 (pKa)
- 16.22±0.30(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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UPCDC30245 C화학적 특성, 용도, 생산
Biochem/physiol Actions
UPCDC30245 is an allosteric inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). p97 is an integral component of the ubiquitin fusion degradation (UFD) pathway. It plays a role in degradation of misfolded proteins, Golgi membrane reassembly, membrane transport, myofibril assembly, autophagosome maturation, and cell division, and is overexpressed in many tumor types. UPCDC30245 has an IC50 value of 27 nM, and has been shown to bind at the junction between the D1 and D2 domains of p97. UPCDC30245 has been used in cryo-ECM to show how such inhibitor binding prevents the confomational changes necessary for p97 function.UPCDC30245 준비 용품 및 원자재
원자재
준비 용품
UPCDC30245 공급 업체
글로벌( 9)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 |
huahero21@sina.com | China | 357 | 55 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9414 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 |
3007606172@qq.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24131 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 |
cindy.huang@synzest.com | China | 12007 | 58 |