3,4,5-Trifluorophenylboronic acid
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3,4,5-Trifluorophenylboronic acid 속성
- 녹는점
- 290-295 °C (lit.)
- 끓는 점
- 263.6±50.0 °C(Predicted)
- 밀도
- 1,087g/cm
- 굴절률
- 1,423-1,425
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 18.43g/L
- 산도 계수 (pKa)
- 6.54±0.11(Predicted)
- 물리적 상태
- 가루
- 색상
- 갈색을 띤 노란색
- BRN
- 7371914
- InChIKey
- UHDDEIOYXFXNNJ-UHFFFAOYSA-N
- CAS 데이터베이스
- 143418-49-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | N-Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 51/53-36-22-36/37/38 | ||
안전지침서 | 61-26-37/39-36 | ||
유엔번호(UN No.) | 3077 | ||
WGK 독일 | 3 | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29163990 |
3,4,5-Trifluorophenylboronic acid C화학적 특성, 용도, 생산
개요
3,4,5-Trifluorophenylboronic acid is an arylboronic acid compound used in organic synthesis and as a reaction reagent. It can be used as a catalyst to catalyse the direct amidation of amino acid derivatives and the direct polycondensation of carboxylic acids and amines; it can also be used in the formation of new 1:1 co-crystals with urea C6H4BF3O2-CH4N2O components.화학적 성질
Tan powder용도
Intermediates of Liquid CrystalsSynthesis
Add 42mmol (10.08g) of magnesium chips into a 1000mL four-necked flask, add 2 pieces of iodine, and then add 200mL of anhydrous 2-methyltetrahydrofuran, heat the temperature to 50°C, and then slowly let it cool down to 40°C. And then drip 4-5mL of 3,4,5-trifluorobromobenzene 84.4g (0.4mol) and 50mL 2-methyltetrahydrofuran mixed solution, trigger the Grignard reaction, the temperature will rise rapidly after the reaction is initiated, use The temperature is lowered to 10-15°C in an ice-water bath, and a mixture (1) composed of 3,4,5-trifluorobromobenzene 84.4g (0.4mol) and 50mL 2-methyltetrahydrofuran (1), trimethyl borate is added dropwise. A mixture of 44 grams (0.42 mol) of ester and 50 mL of 2-methyltetrahydrofuran (2).The speed of the mixed solution (1) and the mixed solution (2) is kept the same, the dropping speed is controlled, and the dropping temperature is kept at 10-15°C . After the dropping is completed, the reaction is continued at room temperature for 8 hours.After the reaction is over, the reaction solution is slowly poured into dilute hydrochloric acid, and after the addition is complete, stir for 0.5-1.5h, separate the liquids, and then extract the aqueous phase twice, combine the organic phases, dry with anhydrous sodium sulfate, spin dry, and Recrystallization of ethyl chloride gave 3,4,5-Trifluorophenylboronic acid with a yield of 78% and a content of 99.6%.3,4,5-Trifluorophenylboronic acid 준비 용품 및 원자재
원자재
준비 용품
3,4,5-Trifluorophenylboronic acid 공급 업체
글로벌( 477)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shandong Promise New Material Co.,Ltd. | +86-18678104048 +86-15305334460 |
johnwang@promisechemical.com | China | 89 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 |
info@spring-chem.com | China | 2068 | 57 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
China Synchem Technology Co.,Ltd. | +86-0552-4929304 +86-18055277008 |
wangxuhui1985@126.com | China | 55 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
3,4,5-Trifluorophenylboronic acid 관련 검색:
붕산트리메틸 보릭산트리이소프로필에스테르 페닐붕산 트라이뷰틸 붕산 보린산
2,3,4,5,6-PENTAFLUOROBENZENEBORONIC ACID
4-Fluorobenzeneboronic acid
3,5-Difluorophenylboronic acid
2,3,4,5-TETRAFLUOROBENZENEBORONIC ACID
2,4,6-TRIFLUOROPHENYLBORONIC ACID
5-Bromo-2,3,4-Trifluorophenylboronic acid
2,3,6-TRIFLUOROPHENYLBORONIC ACID
2,3,6-Trifluorophenylboronic acid
2,3,4-Trifluorophenylboronic Acid (contains varying amounts of Anhydride),4-TRIFLUOROPHENYLBORONIC ACID,2,3,4-TRIFLUOROPHENYLBORONIC ACID
6-Bromo-2,3,4-Trifluorophenylboronic acid
2,4,5-TRIFLUOROPHENYLBORONIC ACID
2,4,5-TRIFLUOROPHENYLBORONIC ACID,2,3,5-TRIFLUOROPHENYLBORONIC ACID
2,4,5-Trifluorophenylboronic acid