Chlorphenesin carbamate

Chlorphenesin carbamate 구조식 이미지
카스 번호:
886-74-8
상품명:
Chlorphenesin carbamate
동의어(영문):
maolate;U-19646;Kalsont;rinlaxer;NSC 82943;Kolpicortin-sine;Chlorphensin carbamate;CHLORPHENESIN CARBAMATE;laChlorphenesin Carbamate;p-Chlorophenyl-α-glyceryl ether carbamate
CBNumber:
CB6493622
분자식:
C10H12ClNO4
포뮬러 무게:
245.66
MOL 파일:
886-74-8.mol
MSDS 파일:
SDS

Chlorphenesin carbamate 속성

녹는점
89-91°
밀도
1.3336 (rough estimate)
굴절률
1.6000 (estimate)
저장 조건
-20°C, Inert atmosphere
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
CAS 데이터베이스
886-74-8(CAS DataBase Reference)

안전

유해 물질 데이터 886-74-8(Hazardous Substances Data)
독성 LD50 orally in rats: 748 mg/kg; i.v. in mice: 239 mg/kg (Cass, Frederick)
기존화학 물질 KE-05812

Chlorphenesin carbamate C화학적 특성, 용도, 생산

용도

'Muscle relaxant

정의

ChEBI: The carbamate ester of the primary hydroxy group of chlorphenesin. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm.

일반 설명

Chlorphenesin carbamate,3-(p-chlorophenoxy)-1,2-propanediol 1-carbamate (Maolate),is the p-chloro substituted and 1-carbamate derivativeof the lead compound in the development of this group ofagents, mephenesin. Mephenesin is weakly active and shortlivedbecause of facile metabolism of the primary hydroxylgroup. Carbamylation of this group increases activity. p-Chlorination increases the lipophilicity and seals off thepara position from hydroxylation. Metabolism, still fairlyrapid, involves glucuronidation of the secondary hydroxylgroup. The biological half-life in humans is 3.5 hours.

Chlorphenesin carbamate 준비 용품 및 원자재

원자재

준비 용품


Chlorphenesin carbamate 공급 업체

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