BIOTIN HPDP

BIOTIN HPDP 구조식 이미지
카스 번호:
129179-83-5
상품명:
BIOTIN HPDP
동의어(영문):
Biotin Impurity 31;Pyridyldithiol-biotin;Biotin HPDP,BiotinHPDP;Pyridyldisulfide-biotin;Ciprofibrate Impurity 6;Macamide Impurity 11(Biotin HPDP);N-[6-(Biotinamido)hexyl]-3'-(2'-pyridyldithio)propionamide;N-[6-(BiotinaMido)hexyl]-3`-(2`-pyridyldithio)propionaMide(Biotin-HPDP);(3aS,4S,6aR)-Hexahydro-2-oxo-N-[6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]-1H-thieno[3,4-d]imidazole-4-pentanamide;5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(6-(3-(pyridin-2-yldisulfanyl)propanamido)hexyl)pentanamide
CBNumber:
CB6500704
분자식:
C24H37N5O3S3
포뮬러 무게:
539.78
MOL 파일:
129179-83-5.mol

BIOTIN HPDP 속성

녹는점
160-163°C
끓는 점
876.0±65.0 °C(Predicted)
밀도
1.28
저장 조건
-20°C Freezer
용해도
insoluble in H2O; ≥101.4 mg/mL in DMSO; ≥8.29 mg/mL in EtOH with ultrasonic
산도 계수 (pKa)
13.90±0.40(Predicted)
물리적 상태
powder to crystal
색상
흰색에서 밝은 노란색

안전

HS 번호 2934.99.4400

BIOTIN HPDP C화학적 특성, 용도, 생산

개요

Biotin-HPDP is a sulfhydryl-reactive biotinylation reagent that forms a reversible disulfide linkage. It is used to label protein cysteines and other substrates that contain sulfhydryl groups. Biotin-HPDP is also used in the biotin switch technique to tag S-nitrosylated (SNO) proteins, following reduction of SNO groups to thiols. Compounds that are tagged with biotin interact avidly with streptavidin-coupled beads, fluorophores, enzymes, etc. The interaction of biotin-HPDP with substrates containing sulfhydryl groups is easily performed at pH 6.5 to 7.5 in buffers such as PBS. The disulfide linkage that is formed between avidin and substrate can later by cleaved by a reducing agent, like dithiothreitol.

화학적 성질

Pale Yellow Solid

용도

This compounds reacts specifically with thiol groups.

BIOTIN HPDP 준비 용품 및 원자재

원자재

준비 용품


BIOTIN HPDP 공급 업체

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Aladdin Scientific
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Amadis Chemical Company Limited
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