MOEXIPRIL HYDROCHLORIDE

MOEXIPRIL HYDROCHLORIDE 구조식 이미지
카스 번호:
82586-52-5
상품명:
MOEXIPRIL HYDROCHLORIDE
동의어(영문):
CI-925;Perdix;SPM-925;Univasc;Fempress;RS-10085;RS-10085-197;MOEXIPRIL HYDROCHLORIDE;Moexipril HCl (RS-10085);Moexipril hydrochloride, >=99%
CBNumber:
CB6500845
분자식:
C27H35ClN2O7
포뮬러 무게:
535.03
MOL 파일:
82586-52-5.mol
MSDS 파일:
SDS

MOEXIPRIL HYDROCHLORIDE 속성

녹는점
141-1610C
알파
D23 +34.2° (c = 1.1 in ethanol)
저장 조건
2-8°C
용해도
H2O: 가용성32mg/mL
물리적 상태
가루
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 N
위험 카페고리 넘버 50
안전지침서 60
유엔번호(UN No.) UN 3077 9/PG 3
WGK 독일 3
RTECS 번호 NW7174500
HS 번호 2933492250
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H400 수생생물에 매우 유독함 수생 환경유해성 물질 - 급성 구분 1 경고 GHS hazard pictograms P273, P391, P501
예방조치문구:
P273 환경으로 배출하지 마시오.
P391 누출물을 모으시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
0
3 0

MOEXIPRIL HYDROCHLORIDE C화학적 특성, 용도, 생산

개요

Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for the treatment of hypertension as a monotherapy and as a second-line therapy in combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril is a prodrug that is converted in the liver to its diacid moexiprilat which is the active agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril although its effectiveness in reduction of blood pressure in hypertensive patients is similar to that seen with enalapril. It is orally active with a rapid onset and prolonged duration of action. Excellent tolerability has been reported. Moexipril is distinguished by its lower cost than other marketed ACE inhibitors.

화학적 성질

Crystalline Solid

용도

Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril

위험도

Moderately toxic by ingestion.

생물학적 활성

Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

MOEXIPRIL HYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품


MOEXIPRIL HYDROCHLORIDE 공급 업체

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1015@dideu.com China 2263 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 29831 58

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