ChemicalBook
Chinese English Japanese Germany Korea

MOEXIPRIL HYDROCHLORIDE

MOEXIPRIL HYDROCHLORIDE 구조식 이미지
카스 번호:
82586-52-5
상품명:
MOEXIPRIL HYDROCHLORIDE
동의어(영문):
CI-925;Perdix;Univasc;SPM-925;Fempress;RS-10085;RS-10085-197;MOEXIPRIL HYDROCHLORIDE;Moexipril hydrochloride, >=99%;Moexipril Hydrochloride (100 mg)
CBNumber:
CB6500845
분자식:
C27H35ClN2O7
포뮬러 무게:
535.03
MOL 파일:
82586-52-5.mol

MOEXIPRIL HYDROCHLORIDE 속성

녹는점
141-1610C
알파
D23 +34.2° (c = 1.1 in ethanol)
저장 조건
2-8°C
용해도
H2O: soluble32mg/mL
물리적 상태
powder
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 N
위험 카페고리 넘버 50
안전지침서 60
유엔번호(UN No.) UN 3077 9/PG 3
WGK 독일 3
RTECS 번호 NW7174500
HS 번호 2933492250
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H400 수생생물에 매우 유독함 수생 환경유해성 물질 - 급성 구분 1 경고 P273, P391, P501
예방조치문구:
P273 환경으로 배출하지 마시오.

MOEXIPRIL HYDROCHLORIDE C화학적 특성, 용도, 생산

개요

Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for the treatment of hypertension as a monotherapy and as a second-line therapy in combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril is a prodrug that is converted in the liver to its diacid moexiprilat which is the active agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril although its effectiveness in reduction of blood pressure in hypertensive patients is similar to that seen with enalapril. It is orally active with a rapid onset and prolonged duration of action. Excellent tolerability has been reported. Moexipril is distinguished by its lower cost than other marketed ACE inhibitors.

화학적 성질

Crystalline Solid

Originator

Warner-Lambert (U.S.A.)

용도

Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril

용도

Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme inhibitor (ACE) with IC50 of 0.041 μM, which is used for the treatment of hypertension and congestive heart failure

상표명

Univasc (Schwarz Pharma).

위험도

Moderately toxic by ingestion.

생물학적 활성

Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

MOEXIPRIL HYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품


MOEXIPRIL HYDROCHLORIDE 공급 업체

글로벌( 85)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15881 69
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1940 70
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32362 50
XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
86-712-2580625 QQ:1791901229 1791901229@qq.com China 9078 52
China Langchem Inc. 0086-21-58956006,021-58950017
0086-21-58956100 sales@langchem.com China 1329 57
Shanghai Everchem Co., Ltd 86-29-81325371
+86-29-81325373 info@everchem.cn China 86 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd +86 (21) 51613915
+86 (21) 51613951 sales@sunwaypharm.com China 9894 57

MOEXIPRIL HYDROCHLORIDE 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved