ChemicalBook >제품 카탈로그 >NSC 23766 TETRAHYDROCHLORIDE

NSC 23766 TETRAHYDROCHLORIDE

NSC 23766 TETRAHYDROCHLORIDE 구조식 이미지

카스 번호:: 733767-34-5

상품명:: NSC 23766 TETRAHYDROCHLORIDE

동의어(영문):: CS-594;CS-1187;NSC 23766;NPEC-caged-(1S;NSC23766;NSC 23766;NSC-23766 free base;NSC 23766 TETRAHYDROCHLORIDE;N6-(2-(5-(Diethylamino)pentan-2-ylamino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine;4,6-Quinolinediamine, N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-;N6-[2-(4-Diethylamino-1-methylbutylamino)-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine tetrahydrochloride

CBNumber:: CB6504010

분자식:: C24H35N7

포뮬러 무게:: 421.58

MOL 파일:: 733767-34-5.mol

속성

안전

용도

공급 업체 95

NSC 23766 TETRAHYDROCHLORIDE 속성

저장 조건: Desiccate at RT

용해도: DMSO(50mg/ml)에 용해됨; 물(50mg/ml)

물리적 상태: 백색 분말 고체.

색상: 하얀색

수용성: 물에 용해됩니다.

감도: Light Sensitive & Hygroscopic

안정성: 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 증류수에 용해된 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.

안전

NSC 23766 TETRAHYDROCHLORIDE C화학적 특성, 용도, 생산

용도

The compound blocks activation by the guanine nucleotide exchange factors Trio and Tiam1, but does not affect interactions with RhoA or Cdc42. NSC23766 blocks ADP-mediated platelet aggregation. Inhibition of Rac1 by NSC23766 restores sensitivity to trastuzumab by restoring down-regulation of ErbB2. Membrane type 1-matrix metalloproteinases (MT-1MMP) expression in CB CD34+ cells has been reported to decrease in the presence of NSC 23766. Silveta compress investigations indicate that NSC 23766 depolarizes endomembrane cycling, altered polar adhesive secretion, and tip growth.

생물학적 활성

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC 50 ~ 50 μ M) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and reported to reverse tumor cell phenotyes in prostate cancer cells.

NSC 23766 TETRAHYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품

NSC 23766 TETRAHYDROCHLORIDE 공급 업체

글로벌( 95)공급 업체

공급자	전화	이메일	국가	제품 수	이점
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
QINGDAO CARELONGPHARMATECH CO.,LTD	0532-0532-88191853 13061484198	sales@carelongchem.com	China	400	57
Shanghai Aladdin Bio-Chem Technology Co.,LTD	18521735133 18521732826;	market@aladdin-e.com	China	25015	65
TargetMol Chemicals Inc.	021-33632979 15002134094	marketing@targetmol.com	China	7934	58
AdooQ Bioscience CHINA	025-58849295 18951903616;	info@adooq.cn	China	2989	60

NSC 23766 TETRAHYDROCHLORIDE 관련 검색:

Motesanib 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE NSC697923 MIF Antagonist, ISO-1 GSK-3β Inhibitor XVIII Pictilisib JNJ-10198409 NSC23005 Sodium Chk2 Inhibitor Trolox NSC632839hydrochloride KENPAULLONE NSC5844 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide NSC-348884 NSC-41589 NSC59984