ALMITRINE

ALMITRINE 구조식 이미지
카스 번호:
27469-53-0
상품명:
ALMITRINE
동의어(영문):
S-2620;ALMITRINE;AlMitrine Mesylate;ALMITRINE USP/EP/BP;Almitrine dimethanesulfonic acid;2,4-Bis(allylamino)-6-[4-[bis(p-fluorophenyl)methyl]-1-piperazinyl]-s-triazine;1-[2,4-Bis(allylamino)-1,3,5-triazin-6-yl]-4-[bis(4-fluorophenyl)methyl]piperazine;6-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]-N,N'-di(2-propenyl)-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, 6-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-N2,N4-di-2-propen-1-yl-
CBNumber:
CB6667472
분자식:
C26H29F2N7
포뮬러 무게:
477.55
MOL 파일:
27469-53-0.mol

ALMITRINE 속성

녹는점
181°
밀도
1.2278 (estimate)
물리적 상태
고체
물리적 상태
단단한 모양

안전

독성 LD50 ipr-mus: 390 mg/kg DRFUD4 3,717,78

ALMITRINE C화학적 특성, 용도, 생산

용도

Respiratory stimulant.

정의

ChEBI: A triamino-1,3,5-triazine compound having allylamino substituents at the 2- and 4-positions and a 4-(bis(p-fluorophenyl)methyl)-1-piperazinyl group at the 6-position.

World Health Organization (WHO)

Peripheral neuropathy has been reported in a few patients receiving almitrine for long periods. The indications for treatment have consequently been restricted in the Federal Republic of Germany. Some other countries have advised doctors to maintain patients under close supervision throughout treatment and to restrict dosage to two out of every three months.

Pharmacology

Almitrine, like doxapram, increases the rate and depth of respiration. In addition, it is believed that it redistributes pulmonary blood circulation, increasing it in alveoli, which leads to relatively better pulmonary ventilation. It has a more prolonged effect than doxapram.

Safety Profile

Poison by intraperitoneal andintravenous routes. When heated to decomposition itemits very toxic fumes of F?? and NOx.

ALMITRINE 준비 용품 및 원자재

원자재

준비 용품


ALMITRINE 공급 업체

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