모노클로로아세트알데히드

모노클로로아세트알데히드 속성

모노클로로아세트알데히드 C화학적 특성, 용도, 생산

화학적 성질

Chloroacetaldehyde is a combustible, colorless liquid with a very sharp, irritating odor.

물리적 성질

Clear, colorless liquid with an irritating, acrid odor

용도

Chloroacetaldehyde is used in the productionof 2-aminothiazole.

정의

ChEBI: Chloroacetaldehyde is acetaldehyde substituted at C-2 by chlorine. It derives from an acetaldehyde.

일반 설명

A clear colorless liquid with a pungent odor. Flash point about 190°F. Corrosive to skin and mucous membranes. Chloroacetaldehyde is very toxic by inhalation.

공기와 물의 반응

Soluble in water. Forms an insoluble hemihydrate at greater than 50% concentration.

반응 프로필

Chloroacetaldehyde polymerizes on standing. At greater than 50% concentration in water, Chloroacetaldehyde forms an insoluble hemihydrate. Sensitive to heat. Reacts with oxidizing agents. Incompatible with acids and water . Burns to give poisonous and irritating gases.

위험도

Corrosive to skin and mucous membranes. TLV: ceiling 1 ppm.

건강위험

Chloroacetaldehyde is a highly toxic andcorrosive compound that can injure the eyes,skin, and respiratory system. Exposure toits vapor at high concentrations can producesevere irritation and impair vision. At lowconcentrations, the vapor can cause irritationand sore eyelids. Brief contact with 40%aqueous solution can result in skin burn anddestruction of tissues. A 0.5% dilute solutioncan still be irritating on skin.
Inhalation of its vapor at the 5-ppm levelcan irritate the eyes, nose, and throat. Ingestionmay result in pulmonary edema. Swallowinga concentrated solution may be fatal.The acute toxicity data are as follows:
LD50 value, intraperitoneal (rats): 2 mg/kg
LD50 value, oral (rats): 23 mg/kg
LD50 value, skin (rabbits): 67 mg/kg
This compound is a mutagen, testing positivein the Ames test.

화재위험

Combustible; flash point (closed cup) 87.8°C (190°F); flash point of 50% aqueous solution 53°C (128°F) (at this concentration it may form insoluble hemihydrate); it forms an explosive mixture with air. Reactions with strong acids and oxidizers are exothermic.

Safety Profile

Suspected carcinogen. Poison by ingestion, skin contact, and intraperitoneal routes. Mutation data reported. Combustible when exposed to heat or flame. Reacts with oxidizing materials. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also ALDEHYDES and CHLORIDES.

잠재적 노출

Chloroacetaldehyde is used as a fungicide; as an intermediate in 2-aminothiazole manufacture; and in bark removal from tree trunks.

Carcinogenicity

Chloroacetaldehyde has been reported to be an inhibitor of DNA synthesis and to form DNA adducts; it is mutagenic in Salmonella typhimurium and in Chinese hamster cells.
Limited in vivo genotoxicity studies with chloroacetaldehyde were negative.

환경귀착

Chemical/Physical. Polymerizes on standing (Windholz et al., 1983).

운송 방법

UN22322-Chloroethanal, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, Inhalation Hazard Zone B.

비 호환성

Heat and water sensitive; concentrations of .50% form insoluble hemihydrate material on contact with water. Reacts with oxidizers, acids. On heating,chloroacetaldehyde releases chlorine fumes. Polymerizable upon standing

폐기물 처리

Incineration, preferably after mixing with another combustible fuel; care must be exercised to assure complete combustion to prevent the formation of phosgene; an acid scrubber is necessary to remove the halo acids produced.

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