페닐레프린 수화염화물
|
|
페닐레프린 수화염화물 속성
- 녹는점
- 143-145 °C(lit.)
- 알파
- -47 º (c=2, H2O)
- 굴절률
- -45.5 ° (C=1, H2O)
- 인화점
- 9℃
- 저장 조건
- 2-8°C
- 용해도
- 물과 에탄올(96%)에 자유롭게 용해됩니다.
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- pK1 8.77; pK2 9.84(at 25℃)
- 색상
- 흰색에서 거의 흰색
- 수소이온지수(pH)
- pH (10g/L, 25℃) : 4.5～5.5
- 수용성
- 21 ºC에서 >=10g/100mL
- Merck
- 14,7286
- BRN
- 4158948
- 안정성
- 흡습성
- LogP
- -0.310
- CAS 데이터베이스
- 61-76-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,T,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38-39/23/24/25-23/24/25-11 | ||
| 안전지침서 | 26-36-37/39-45-36/37-16-7 | ||
| 유엔번호(UN No.) | 3249 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | DO7525000 | ||
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| HS 번호 | 29225090 | ||
| 독성 | LD50 in rats (mg/kg): 17 ±1.1 i.p.; 33 ±2.0 s.c. (Warren, Werner) | ||
| 기존화학 물질 | KE-20631 |
페닐레프린 수화염화물 C화학적 특성, 용도, 생산
개요
R-(-)-Phenylephrine is an adrenergic α1A receptor agonist (Ki = 1.4 μM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 μM, respectively). By stimulating adrenergic α1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine . This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents.화학적 성질
white to almost white crystalline powder용도
(R)-Phenylephrine Hydrochloride is an α-Adrenergic agonist. Mydriatic; decongestant.정의
ChEBI: A hydrochloride that is the monohydrochloride salt of phenylephrine.일반 설명
Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.공기와 물의 반응
May be sensitive to prolonged exposure to air and light. Water soluble.반응 프로필
Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.화재위험
Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.생물학적 활성
α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.색상 색인 번호
Phenylephrine hydrochloride is an alpha-adrenergic agonist, used as a mydriatic and decongestant in eyedrops.Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, intravenous,and intramuscular routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.페닐레프린 수화염화물 준비 용품 및 원자재
원자재
준비 용품
페닐레프린 수화염화물 공급 업체
글로벌( 542)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12452 | 58 |
| Shanghai Aosiris new Material Technology Co., LTD | +8615139564871 |
wrjmoon2000@163.com | China | 350 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Jimi Trading Co., Ltd. | +86 319 5273535 |
bestoneforyou@sina.com | CHINA | 288 | 58 |
페닐레프린 수화염화물 관련 검색:
벤질 알코올 에핀에피린 초산에틸 우르소데옥시콜산 이소프레날린 염산 세노디올 3,4-다이하이드록시-알파-메틸페닐알라닌 페닐레프린 수화염화물
Topotecan hydrochloride
Epinephrine Hydrochloride
CHLOROPHOSPHONAZO III
DL-NORPHENYLEPHRINE HYDROCHLORIDE
N-methyl-5,6-dihydroxyindole
2,2-Dichloro-1-(3-hydroxyphenyl)-ethanone
N-(2-Succinyl) Phenylephrine
Phenylephrine Impurity 32
N-ACETYL-4-BENZOQUINONE IMINE
1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline