ChemicalBook >제품 카탈로그 >Tomatidine hydrochloride

Tomatidine hydrochloride

Tomatidine hydrochloride 구조식 이미지

카스 번호:: 6192-62-7

상품명:: Tomatidine hydrochloride

동의어(영문):: TOMATIDINE HCL;TOMATIDINE HCL(RG);TOMATIDINE HYDROCHLORIDE;ToMatidin Hydrochloride, >85%;Tomatidine Hydrochloride, >5alpha-Tomatidan-3beta-ol HCl;Tomatidine, Hydrochloride, >85%;5α-Tomatidan-3β-ol hydrochloride;SPIRPSOLAN-3-OL-(3B,5A,22B,25C) HCL;3β-Hydroxy-5α-tomatidane hydrochloride

CBNumber:: CB6774105

분자식:: C27H46ClNO2

포뮬러 무게:: 452.11

MOL 파일:: 6192-62-7.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 106

Tomatidine hydrochloride 속성

녹는점: 281-284°C (dec.)

저장 조건: 2-8°C

용해도: 메탄올(약간)에 용해됨

물리적 상태: 회백색 고체

색상: 흰색에서 황백색까지

BRN: 3920740

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

안전지침서	22-24/25
WGK 독일	3

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
2		0

Tomatidine hydrochloride C화학적 특성, 용도, 생산

화학적 성질

Off-White Solid

용도

Tomatidine hydrochloride is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine.Tomatidine protects against muscle atrophy and boosting muscle growth (see also Ursolic Acid).

생물학적 활성

Tomatidine is a steroidal alkaloid that has been found in the skins and leaves of tomatoes. It suppresses NF-κB signaling in LPS-stimulated macrophages, blocking induced expression of inducible nitric oxide synthase (iNOS) and COX-2. Tomatidine inhibits acid sphingomyelinase activity by 84.2% when used at a concentration of 10 mM. It also has antibacterial properties, preferentially blocking the replication of S. aureus variants that are pathogenic in cystic fibrosis over normal strains (MICs = 0.12 and >16 μg/ml, respectively). It prevents skeletal muscle atrophy associated with fasting or spinal cord injury in mice. Tomatidine has also been used as a negative control for cyclopamine (Item No. 11321) in studies involving signaling mediated by the hedgehog pathway.

Mode of action

Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. It activates autophagy either in mammal cells or C elegans.

Tomatidine hydrochloride 준비 용품 및 원자재

원자재

준비 용품

Tomatidine hydrochloride 공급 업체

글로벌( 106)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253	jancyzheng@gcgreenpure.com	China	952	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	nutrabiotech@outlook.com	China	300	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58

Tomatidine hydrochloride 관련 검색:

옥타데킬아민 수화염화물 디이소부틸아민 염화수소 Xanthiside Lycopene Apo-12'-lycopenal L-Hyoscyamine menisdaurin daurisoline TOMATINE TOMATIDINE 2-Propylpiperidine hydrochloride Cyclopentamine 2-PIPERIDINOL Dihydrocholesterol 2-AMINONONADECANE Tomatidine hydrochloride 3-PIPERIDIN-2-YL-PROPAN-1-OL cyclopentamine hydrochloride