1-AZAKENPAULLONE
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1-AZAKENPAULLONE 속성
- 녹는점
- >290°C (dec.)
- 끓는 점
- 648.8±50.0 °C(Predicted)
- 밀도
- 1.655±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: >10mg/mL
- 산도 계수 (pKa)
- 13.36±0.20(Predicted)
- 물리적 상태
- 황갈색 고체
- 색상
- 회갈색
- InChI
- InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
- InChIKey
- NTSBZVCEIVPKBJ-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Br)C=C2)C2CC(=O)NC3=CC=CN=C3C1=2
안전
| WGK 독일 | 2 |
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1-AZAKENPAULLONE C화학적 특성, 용도, 생산
화학적 성질
Tan Solid용도
A selective inhibitor of glycogen synthase kinase-3β.일반 설명
A Kenpaullone (>Cat. No. 422000) analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM). Displays over 100-fold greater selectivity over Cdk1/cyclin B and Cdk5/p25 (IC50 = 2.0 μM and 4.2 μM, respectively). The solid form of this compound (Cat. No. 191500) is also available.효소 저해제
This cell-permeable protein kinase inhibitor (FW = 328.17 g/mol; CAS 676596-65-9: Solubility: 66 mg/mL DMSO; <1 mg/mL H2O), also named 9-bromo-7,12-dihydro-pyrido[3,2’:2,3]azepino[4,5-b]indol-6(5H)-one, selectively and potently targets glycogen synthase kinase 3β, or GSK3β (IC50 = 18 nM) with 100x less inhibitory action against cyclin-dependent kinases (CDKs). 1-Azakenpaullone has become a gold standard for GSK3 inhibition.1-AZAKENPAULLONE 준비 용품 및 원자재
원자재
준비 용품
1-AZAKENPAULLONE 공급 업체
글로벌( 84)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Meike meditech (Foshan) Co.,Ltd | +86-0757-22239986 +86-18029359586 |
sales@mkmeditech.com | China | 1134 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29271 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |