1,2,3-트라이클로로프로페인(1,2,3-트리클로로프로판) C화학적 특성, 용도, 생산
개요
1,2,3-Trichloropropane is a synthetic chemical that is also known as allyl trichloride, glycerol trichlorohydrin, and trichlorohydrin. It is a colourless, heavy liquid with a sweet but strong chloroform-like odour and is combustible. It is slightly soluble in water but soluble in chloroform, diethyl ether, and ethanol. On contact with heat/ fire, It releases off irritating or toxic fumes (or gases). It evaporates very quickly and small amounts dissolve in water. It is mainly used to make other chemicals. 1,2,3-Trichloropropane was used in the past mainly as a solvent and extractive agent, including as a paint and varnish remover and as a cleaning and degreasing agent. It is now used mainly as a chemical intermediate, for example, in the production of polysulphone liquid polymers, dichloropropene and hexafluoropropylene and as a cross-linking agent in the synthesis of polysulphides.
화학적 성질
1,2,3-Trichloropropane is a colorless liquid with a strong acid odor. slightly soluble in water; dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. autoign temp 580F (304°C). Combustible.
물리적 성질
Clear, colorless liquid with a strong, chloroform-like odor
용도
1,2,3-Trichloropropane is used as a solventand as an intermediate in organic synthesis.
일반 설명
Colorless liquid with a strong acid odor. Denser than water and slightly soluble in water. Hence sinks in water.
반응 프로필
1,2,3-Trichloropropane is sensitive to prolonged exposure to light. Sensitive to heat. May react with active metals, strong caustics and oxidizing agents. Attacks some plastics, rubber and some coatings .
건강위험
Inhalation of its vapors can produce depres sion of the central nervous system, which canprogress to narcosis and convulsion as theconcentration increases. A 30-minute expo sure to a 5000-ppm concentration causedconvulsions in rats. Acute as well as chronicexposure to high concentrations can causeliver damage. 1,2,3-Trichloropropane is moretoxic than its 1,1,1-isomer. Acute oral tox icity is moderate, with LD50 values rang ing between 300 and 550 mg/kg in differentspecies of experimental animals. The liquidis a strong irritant to the eyes.
화재위험
Combustible liquid; flash point (closed cup)
73°C (164°F), (open cup) 82°C (180°F).
Vapors of 1,2,3-trichloropropane form explo sive mixtures with air, with LEL and UEL
values of 3.2% and 12.6% by volume in air,
respectively. The compound reacts vigorously
with alkali metals, powdered magnesium, or
aluminum; caustic alkalies; and oxidizers.
Safety Profile
Confirmed carcinogen.
Poison by ingestion. Moderately toxic by
inhalation and skin contact. Experimental
reproductive effects. A skin and severe eye
irritant. Mutation data reported. Moderately
flammable by heat, flames (sparks), or
powerful oxidizers. See also ALLYL
COMPOUNDS and CHLORINATED
HYDROCARBONS, ALIPHATIC. When
heated to decomposition it yields hghly
toxic Cl-. To fight fre, use water (as a
blanket), spray, mist, dry chemical.
잠재적 노출
Trichloropropane dissolves oils, fats,
waxes, chlorinated rubber; and numerous resins; it is used
as a paint and varnish remover; a solvent; and a degreasing
agent.
Carcinogenicity
1,2,3-Trichloropropane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
환경귀착
Chemical/Physical. The hydrolysis rate constant for 1,2,3-trichloropropane at pH 7 and 25 °C
was determined to be 1.8 x 10
-6/h, resulting in a half-life of 43.9 yr (Ellington et al., 1988). The
hydrolysis half-lives decrease at varying pHs and temperature. At 87 °C, the hydrolysis half-lives
at pH values of 3.07, 7.12, and 9.71 were 21.1, 11.6, and 0.03 d, respectively (Ellington et al.,
1986). By analogy to 1,2-dibromo-2-chloropropane, the following hydrolysis products would be
formed: 2,3-dichloro-1-propanol, 2,3-dichloropropene, epichlorohydrin, 1-chloro-2,3-
dihydroxypropane, glycerol, 1-hydroxy-2,3-propylene oxide, 2-chloro-3-hydroxypropene, and
HCl (Kollig, 1993).
The volatilization half-life of 1,2,3-trichloropropane (1 mg/L) from water at 25 °C using a
shallow-pitch propeller stirrer at 200 rpm at an average depth of 6.5 cm was 56.1 min (Dilling,
1977).
운송 방법
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
비 호환성
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Violent decomposition
with chemically active metals; strong bases. Keep away
from chlorinated rubber, resins and waxes; and sunlight.
폐기물 처리
Incineration, preferably after
mixing with another combustible fuel. Care must be exercised
to assure complete combustion to prevent the formation
of phosgene. An acid scrubber is necessary to remove
the halo acids produced.
1,2,3-트라이클로로프로페인(1,2,3-트리클로로프로판) 준비 용품 및 원자재
원자재
준비 용품
