Epothilone A

Epothilone A 구조식 이미지
카스 번호:
152044-53-6
상품명:
Epothilone A
동의어(영문):
CS-555;CS-1899;Epothile;Ebomycin A;Epothilon A;Epothilone-S;EPOTHILONE A;(-)-EPOTHILONE A;Epothilone A (Epo A);Ixabepilone Impurity 5
CBNumber:
CB6972280
분자식:
C26H39NO6S
포뮬러 무게:
493.66
MOL 파일:
152044-53-6.mol

Epothilone A 속성

녹는점
95℃
알파
D21 -47.1° (c = 1.0 in methanol)
끓는 점
683.3±55.0 °C(Predicted)
밀도
1.143
저장 조건
-20°C
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
산도 계수 (pKa)
13.57±0.70(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안정성
Stable under recommended storage conditions., Stable Under Recommended Storage C

안전

WGK 독일 3

Epothilone A C화학적 특성, 용도, 생산

용도

The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, B isolated from Sorangium cellulosum was associated with cell cycle arrest at G2/M transition and apoptosis that was resisted with overexpression of β-tubulin and P-glycoprotein in human bladder carcinoma cell.

정의

ChEBI: An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer).

Epothilone A 준비 용품 및 원자재

원자재

준비 용품


Epothilone A 공급 업체

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